Glycerol is a valuable by-product in the biodiesel industries. However, the increase in biodiesel production resulted in an excess production of glycerol, with a limited market compared to its availability. Precisely because glycerol became a waste to be disposed of, the costs of biodiesel production have reduced. From an environmental point of view, identifying reactions that can convert glycerol into new products that can be reused in different applications has become a real necessity. According to the unique structural characteristics of glycerol, transformation processes can lead to different chemical functionalities through redox reactions, dehydration, esterification, and etherification, with the formation of products that can be applied both at the finest chemical level and to bulk chemistry.