The estimation of the solar resource on certain surfaces of the planet is a key factor in deciding where to establish solar energy collection systems. This research uses a mathematical model based on easy-access geographic and meteorological information to calculate total solar radiation at ground surface. This information is used to create a GIS analysis of the State of Nuevo León in Mexico and identify solar energy opportunities in the territory. The analyzed area was divided into a grid and the coordinates of each corner are used to feed the mathematical model. The obtained results were validated with statistical analyses and satellite-based estimations from the National Aeronautics and Space Administration (NASA). The applied approach and the results may be replicated to estimate solar radiation in other regions of the planet without requiring readings from on-site meteorological stations and therefore reducing the cost of decision-making regarding where to place the solar energy collection equipment.