The traditional development mode for social and economic progress has resulted in crises and challenges; therefore, various countries have begun to actively explore sustainable development. As a developing country, China has outstanding environmental problems. However, there are not many empirical studies on the influencing factors of sustainable supply chain in domestic enterprises. Therefore, according to the manufacturing industry in China, a hypothesis model of influencing factors of sustainable supply chain management is set up. The sustainable supply chain practice is based on three dimensions: economic sustainability, environmental sustainability, and social sustainability. The influencing factors of sustainable supply chain include internal management cognition, industry pressure, consumer pressure, and government participation. A structural equation model was used to analyze the questionnaire data of 167 enterprises in Beijing, China. The results show that internal management cognition and government participation has a direct effect on the sustainable supply chain management practice, and internal management cognition has a strong positive influence. Consumer pressure and industry pressure have a small positive impact on internal management cognition, while the effect of government participation on industry pressure is very significant.