Tourists’ intentions show many changing dynamics, both in terms of destination and accommodation selection. These changes in dynamics are seasonal and significantly affected by trends. Therefore, after an infectious disease outbreak, as is the case with COVID-19 caused by a new coronavirus called SARS-CoV-2, these dynamics change on an entirely different level and are so far unknown. Contextual research was conducted to define and analyze the impacts of SARS-CoV-2 on Azores residents’ tourism accommodations plans in 2020 by examining their intentions. The most frequent choice was to spend 2020 vacations at the vacation residences of family or friends (24.3%), followed by approximately 20% who chose three- to four-star hotels. A considerable increase in rural tourism accommodation selection intentions was noticed, obtaining the third position with 13.7%, followed by local accommodation (guest house) with 12.1% of the selection intentions. The study concludes that there are massive consequences of the SARS-CoV-2 crisis at the level of holiday choices and social isolation concerns for this ultra-peripheral territory.