The rapid increase in urbanization has brought about a great deal of ecological problems, and thus the systematic protection of the environment is vital. Ecological security patterns are important for maintaining regional ecological stability and sustainable urban development. Human disturbance is a key factor affecting the stability and sustainable development of ecosystems. This paper constructs an ecological security pattern and evaluates the degree of human disturbance in Fuzhou City. Through a comprehensive analysis of both of these factors, the ecological priority restoration areas in Fuzhou were identified. The study shows that (1) there are 40 ecological source areas in Fuzhou, with a total area of 4556.48 km2; 83 ecological corridors, with a total distance of 179.33 km; and 30 ecological nodes. (2) The human disturbance degree score in the study area is between 0 and 0.8. The degree of human disturbance forms two larger major cores in Cangshan District, Gulou District, and Fuqing City. (3) The scores for the degree of human disturbance with ecological sources range from 0 to 0.42. The high-priority areas in the study area are distributed at the edges of ecological sources and form two high-scoring aggregation areas in Fuqing City and Jinan District. These corridors have a high degree of human disturbance with scores between 0 and 0.56. The I and II priority areas are mostly found in longer corridors in Fuqing City and Cangshan District near coastal or urban centers, and the III priority areas are mainly distributed in ecological corridors near the inland. The human disturbance degree scores of the nodes range from 0.01 to 0.27, and the nodes with higher grades were mainly distributed in the northeast, southeast, northwest and southwest of the study area.