Institutions of higher learning have made persistent efforts to provide students with a high-quality education. Educational data mining (EDM) enables academic institutions to gain insight into student data in order to extract information for making predictions. COVID-19 represents the most catastrophic pandemic in human history. As a result of the global pandemic, all educational systems were shifted to online learning (OL). Due to issues with accessing the internet, disinterest, and a lack of available tools, online education has proven challenging for many students. Acquiring accurate education has emerged as a major goal for the future of this popular medium of education. Therefore, the focus of this research was to identifying attributes that could help in students’ performance prediction through a generalizable model achieving precision education in online education. The dataset used in this research was compiled from a survey taken primarily during the academic year of COVID-19, which was taken from the perspective of Pakistani university students. Five machine learning (ML) regressors were used in order to train the model, and its results were then analyzed. Comparatively, SVM has outperformed the other methods, yielding 87.5% accuracy, which was the highest of all the models tested. After that, an efficient hybrid ensemble model of machine learning was used to predict student performance using NB, KNN, SVM, decision tree, and logical regression during the COVID-19 period, yielding outclass results. Finally, the accuracy obtained through the hybrid ensemble model was obtained as 98.6%, which demonstrated that the hybrid ensemble learning model has performed better than any other model for predicting the performance of students.