Sustainability science focuses on generating and applying knowledge to environmentally sound human development around the world. It requires working toward greater integration of different types of knowledge, ways of knowing, and between academy and society. We contribute to the development of approaches for learning from indigenous knowledge, through enhanced understanding of the system of values, meanings, and relationships afforded by indigenous arts. We focus on a long-term, participatory action research project developed for the revitalization of weaving knowledge among three Kawaiwete (also known as Kaiabi) indigenous groups in the Amazon. The problem was originally defined by indigenous communities, concerned with the erosion of weaving knowledge of basketry and textiles among men and women. Methods for coproduction of knowledge included dialogical methods and tools, indigenous-led strategies, and quantitative and qualitative approaches across biophysical and social sciences. Longitudinal and cross-sectional studies considered multiple dimensions, scales, and networks of knowledge creation, distribution, and transmission. Innovation and articulation with western systems, along with shamanism, gender, and leadership, were key factors enhancing artistic knowledge resilience. We reflect on lessons learned and implications of this initiative for broadening the understanding of art and science intersections toward a sustainable future.