Found an issue? Give us feedback

https://pubmed.ncbi....arrow_drop_down

https://pubmed.ncbi.nlm.nih.go...

Article . 1995

Data sources: Europe PubMed Central

Select content type to embed

All Research products

arrow_drop_down

<script type="text/javascript">
<!--
document.write('<div id="oa_widget"></div>');
document.write('<script type="text/javascript" src="https://beta.openaire.eu/index.php?option=com_openaire&view=widget&format=raw&projectId=undefined&type=result"></script>');
-->
</script>

COPY SCRIPT

For further information contact us at helpdesk@openaire.eu

Flumazenil in alcohol withdrawal.

descriptionPublicationkeyboard_double_arrow_right Article 22 Jun 1995 English Journal:Alcohol and alcoholism (Oxford, Oxfordshire). Supplement, volume 2 (issn: 1358-6173,

Authors: D, Nutt; P, Glue; S, Wilson; S, Groves; N, Coupland; J, Bailey;

pmid: 7748321

Flumazenil in alcohol withdrawal.

- Summary
- Subjects
- Metrics

Abstract

This is a preliminary study to explore the theory that there may be abnormalities of the benzodiazepine receptor, or a possible endogenous inverse agonist ligand in alcohol withdrawal. The benzodiazepine antagonist flumazenil was administered to 8 alcoholics in early withdrawal in a double blind placebo controlled design. Self ratings of mood and physical symptoms, and observer ratings of withdrawal symptoms revealed differences in the effects of flumazenil and placebo. Flumazenil had an immediate slight anxiogenic action which was short-lived. It then appeared to ameliorate withdrawal symptoms, quite markedly in 2 patients.

Keywords

Adult, Flumazenil, Male, Ethanol, Anxiety, Middle Aged, Substance Withdrawal Syndrome, Double-Blind Method, Humans, Female, GABA-A Receptor Antagonists

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	14
	popularity This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.	Average
	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average