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Chemical and Pharmaceutical Bulletin
Article . 1992 . Peer-reviewed
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Chemical and Pharmaceutical Bulletin
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Chemical and Pharmaceutical Bulletin
Article . 1992
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Homeostasis as Regulated by Activated Macrophage. VIII. LPSw(a Lipopolysaccharide from Wheat Flour) Can Regulate Bone Resorption of Chick Embryo.

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Jan 1992Publisher:Pharmaceutical Society of JapanJournal:Chemical and Pharmaceutical Bulletin, volume 40, pages 1,271-1,273 (issn: 0009-2363, eissn: 1347-5223, Copyright policy )
Authors: Hiroyoshi Endo; Takashi Nishizawa; Hiroyuki Inagawa; Takafumi Okutomi; Gen-Ichiro Soma; Den'ichi Mizuno; Kohtaro Kawashima; +1 Authors

doi: 10.1248/cpb.40.1271

pmid: 1394647

Homeostasis as Regulated by Activated Macrophage. VIII. LPSw(a Lipopolysaccharide from Wheat Flour) Can Regulate Bone Resorption of Chick Embryo.

Abstract

The effect of LPSw (a lipopolysaccharide from wheat flour) on the bone resorption of 18-d chick embryonic calvaria was examined in an organ culture following the method of Raisz. Bone was prelabeled in culture medium containing 45Ca and chased in a cold medium. On addition of test samples, labeled calcium was released indicating the grade of bone resorption. LPSw (10-100 ng/ml) stimulated bone resorption, showing an effect comparable to parathyroid hormone (PTH) (1 U/ml). PTH at 1 U/ml decreased the total amount of calcium and phosphorus, while LPSw did not. LPSw is thus assumed to stimulate bone resorption more actively than PTH.

Related Organizations
Keywords

Lipopolysaccharides, Macrophages, Skull, Chick Embryo, Macrophage Activation, Organ Culture Techniques, Animals, Homeostasis, Bone Resorption, Triticum

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
7
Average
Top 10%
Average
gold