A 64-year-old man was referred with upper abdominal ain of 6-months duration. He reported no weight loss, fever r night sweats. Clinical chemistry revealed cholestasis. A iliary stent had previously been inserted at the referring ospital due to bile duct obstruction. EGD, using a side iewing duodenoscope, showed a red fleshy tumour proruding through the papillary orifice (Fig. 1). The biopsy pecimen revealed highly atypical, ovoid to spinde-shaped, ononuclear cells. These were admixed with histiocytes that id not show cytologic atypia, and with large multinuclear steoclast-like giant-cells (Fig. 2). These were mostly posiive for CA19-9. The giant-cells and the mononuclear cells ere negative for epithelial markers but expressed CD68 sugesting a histiocytic differentiation. This case demonstrates n osteoclast-like giant-cell tumour (OCGT) of the pancreas. n additional special feature of our case is the coexistence of anIN I-III as well as early invasive ductal adenocarcinoma hat were found in the resection specimen of the pancreatic ead. In 1968, Rosai first described OCGT in two elderly emales presenting with abdominal masses and weight loss 1]. Similar to our case, there are reports demonstrating the o-existence of OCGT and other pancreatic tumours [2]. The rognosis of the OCGT of the pancreas is generally poor, and sually follows an aggressive clinical course; most patients ie of disease within 1 year [3].