The Weather Research and Forecasting (WRF) model can be used to simulate atmospheric processes ranging from quasi-global to tens of m in scale. Here we employ large-eddy simulation (LES) using the WRF model, with the LES-domain nested within a mesoscale WRF model domain with grid spacing decreasing from 12.15 km (mesoscale) to 0.03 km (LES). We simulate real-world conditions in the convective planetary boundary layer over an area of complex terrain. The WRF-LES model results are evaluated against observations collected during the US Department of Energy-supported Columbia Basin Wind Energy Study. Comparison of the first- and second-order moments, turbulence spectrum, and probability density function of wind speed shows good agreement between the simulations and observations. One key result is to demonstrate that a systematic methodology needs to be applied to select the grid spacing and refinement ratio used between domains, to avoid having a grid resolution that falls in the grey zone and to minimize artefacts in the WRF-LES model solutions. Furthermore, the WRF-LES model variables show large variability in space and time caused by the complex topography in the LES domain. Analyses of WRF-LES model results show that the flow structures, such as roll vortices and convective cells, vary depending on both the location and time of day as well as the distance from the inflow boundaries.