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description Publicationkeyboard_double_arrow_right Article , Journal 1989Publisher:Wiley Authors: G. T. O'Neill; M. H. Kaufman;pmid: 2723605
AbstractThe brief exposure of recently ovulated mouse oocytes to a dilute solution of ethanol in vitro for 1, 3, or 5 min induced a uniform high incidence of parthenogenetic activation. The majority of parthenogenones developed a single haploid pronucleus after the extrusion of a second polar body. The proportionate incidence of this parthenogenetic class was significantly reduced as the duration of ethanol exposure increased from 1 min to 5 min. There was a concomitant increase in the incidence of parthenogenones that developed two haploid pronuclei following failure of extrusion of the second polar body. Cytogenetic analysis of the ethanol‐induced single‐pronuclear haploid parthenogenones at metaphase of the first cleavage division clearly demonstrated that a significant proportion were aneuploid. The incidence of aneuploidy observed was directly related to the duration of ethanol exposure. G‐band analysis of the aneuploid metaphases revealed that the chromosomes were not randomly involved in the malsegregation events. This observation may be a reflection of the relationship of particular chromosomes to the meiotic spindle apparatus rather than on any specific property of the agent to which they were exposed. It is believed that ethanol disrupts the organisation of cytoskeletal elements and, in particular, interferes with the processes of chromosome segregation at the second meiotic division.
Journal of Experimen... arrow_drop_down Journal of Experimental ZoologyArticle . 1989 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu25 citations 25 popularity Average influence Top 10% impulse Average Powered by BIP!
more_vert Journal of Experimen... arrow_drop_down Journal of Experimental ZoologyArticle . 1989 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 1971Publisher:Elsevier BV Authors: Patricia A. Hooper; R. Schneider; Christine J. Benoy;pmid: 5157556
Abstract An orange and an apple juice each containing 250–385 ppm tin were under suspicion of having caused an outbreak of food poisoning in Kuwait in 1967 but did not cause any toxic signs when fed to pigeons, cats and dogs. One cat out of 11 vomited when fed an orange juice containing 540 ppm tin derived from the container, and with juices containing 1370 ppm tin, 20–30% of the cats vomited but none of the dogs was affected. Fruit juices containing 2000 ppm tin caused vomiting in up to 40% of the cats. Modification of orange juices with a high tin content by addition of nitrate or ethanol or by adjustment of the pH from 3 to 6 did not affect the incidence of vomiting. No toxic signs were produced in rats given fruit juices containing added tin salts up to a level of 995 ppm or in rats and cats given aqueous solutions of tin salts (up to 1200 ppm tin) in citric acid. Solid foods containing tin derived from the containers up to the highest level obtainable (470 ppm) had no toxic effect when fed to dogs and cats. Five human volunteers showed no toxic signs after drinking fruit juices containing 498, 540 or 730 ppm tin derived from the containers, but all five had some gastro-intestinal disturbance after drinking a fruit juice containing 1370 ppm tin. A repeat experiment with the latter juice had no effect in four of the volunteers and only mild symptoms in the fifth. In rats and cats, there was no evidence of tin absorption 24 hr after ingestion of fruit juices containing high levels of tin. No tin was recovered from the urine and in the rats 99% was recovered from the faeces. Only minute amounts of tin could be found in the body, apart from the alimentary tract, of a rat that had been given orange juice with a high tin content ad lib. instead of drinking water for 7 days. It is concluded that toxic signs follow the drinking of tin-containing fruit juices by man and cats only with tin levels of approximately 1400 ppm and above, that there is no evidence from these experiments that toxicity is due to the absorption of tin and that the most likely cause is local irritation of the mucous membrane of the alimentary tract.
Food and Cosmetics T... arrow_drop_down Food and Cosmetics ToxicologyArticle . 1971 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu76 citations 76 popularity Top 10% influence Top 10% impulse Average Powered by BIP!
more_vert Food and Cosmetics T... arrow_drop_down Food and Cosmetics ToxicologyArticle . 1971 . Peer-reviewedLicense: Elsevier TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 1988 United KingdomPublisher:Springer Science and Business Media LLC Authors: Gadd, Geoffrey M.; de Rome, Louise;doi: 10.1007/bf00260993
Melanin obtained from Aureobasidium pullulans and Cladosporium resinae was an efficient biosorbent for copper. Copper uptake could be expressed using various adsorption isotherms; melanin from A. pullulans obeyed Freundlich and Langmuir isotherms whereas C. resinae melanin followed the BET isotherm indicating a more complex type of adsorption than in A. pullulans. In general, uptake capacities of melanin were greater than for intact biomass and the higher uptake by pigmented rather than albino biomass could be correlated with the presence of melanin. Cu2+ was less readily desorbed from melanin by dilute mineral acids than from intact biomass and again, the relative ease of Cu2+ desorption from pre-loaded pigmented or albino biomass was correlated with the presence or absence of melanin. Mg2+ and Zn2+ appeared to be the most effective cations for desorption with Na+ and K+ the least effective. The addition of melanin to a coppercontaining culture of the albino strain of A. pullulans resulted in some reduction of toxicity.
Applied Microbiology... arrow_drop_down Applied Microbiology and BiotechnologyArticle . 1988 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu184 citations 184 popularity Top 1% influence Top 1% impulse Average Powered by BIP!
more_vert Applied Microbiology... arrow_drop_down Applied Microbiology and BiotechnologyArticle . 1988 . Peer-reviewedLicense: Springer TDMData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 1977Publisher:Wiley Authors: R. J. S. Duncan;pmid: 853309
Journal of Neurochem... arrow_drop_down Journal of NeurochemistryArticle . 1977 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu1 citations 1 popularity Average influence Average impulse Average Powered by BIP!
more_vert Journal of Neurochem... arrow_drop_down Journal of NeurochemistryArticle . 1977 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 1979Publisher:Elsevier BV William Jeffcoate; M. Herbert; A.G. Hastings; C. P. Walder; M.H. Cullen;In a double-blind, cross-over study of twenty male volunteers intravenous injection of 0.4 mg naloxone prevented the impairment of psychomotor performance induced by low levels of blood alcohol. The possibility that alcohol produces intoxication by stimulating the release of endogenous opioid peptides should be investigated.
add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu154 citations 154 popularity Average influence Top 1% impulse Top 1% Powered by BIP!
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You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 1971Publisher:Wiley Authors: D. G. Smith;pmid: 4106856
Summary.A simple technique for assessing the Gram positivity of dried smears of bacteria is described. Standardized smears on glass slides are decolourized for a specified time and the colorimetric level of crystal violet loss into the decolourizer taken as a measure of Gram positivity. The technique gives comparative values between strains and has been successfully used in several different experimental conditions.
Journal of Applied B... arrow_drop_down Journal of Applied BacteriologyArticle . 1971 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu2 citations 2 popularity Average influence Average impulse Average Powered by BIP!
more_vert Journal of Applied B... arrow_drop_down Journal of Applied BacteriologyArticle . 1971 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2016Publisher:Wiley Authors:Gema Parra;
Gema Parra
Gema Parra in OpenAIREManuel Linares;
Pam Nelmes; Janet Richardson; +1 AuthorsManuel Linares
Manuel Linares in OpenAIREGema Parra;
Gema Parra
Gema Parra in OpenAIREManuel Linares;
Pam Nelmes; Janet Richardson; Jane Grose;Manuel Linares
Manuel Linares in OpenAIREdoi: 10.1111/jan.12900
pmid: 26821875
AbstractAimTo explore the concept of sustainability in nursing using social media as a vehicle for discussion on the topic.BackgroundThere is a need for an increased awareness among nurses of the issues that are crucial for the healthcare sector to prepare for climate change and contribute to sustainable development. However, topics about sustainability and climate change are not a requirement of nursing curricula in Europe; social media provides an opportunity to raise issues and promote discussion.DesignA thematic analysis of a Twitter discussion.MethodsA Twitter discussion session hosted by @WeNurses took place on 24 March 2015 over 1 hour. Data were gathered via this online discussion hosted on Twitter, a social media platform. Following the discussion a thematic analysis of the posted Tweets was conducted.FindingsOne hundred and nineteen people posted nine hundred and ninety six Tweets, a reach of 3,306,368. Tweets broadly followed the questions posted by the team. Several threads related to the sustainable use of healthcare resources and the need to reduce waste was evident. A Word Cloud of the Tweets highlighted prominent words in the discussion: sustainability, nursing/nurses, curriculum, important, waste, practice, resources, student, plastic, health, gloves.ConclusionSocial media is an effective way of engaging nurses and students in a discussion on challenging issues. Sustainability appears to be important for nurses, with a particular emphasis on resource use and the importance of sustainability topics in nurse education.
Journal of Advanced ... arrow_drop_down Journal of Advanced NursingArticle . 2016 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu35 citations 35 popularity Top 10% influence Top 10% impulse Top 10% Powered by BIP!
more_vert Journal of Advanced ... arrow_drop_down Journal of Advanced NursingArticle . 2016 . Peer-reviewedLicense: Wiley Online Library User AgreementData sources: Crossrefadd ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2015 United KingdomPublisher:Elsevier BV Authors: Berthe, Sophie C.F.;Derocles, Stéphane A.P.;
Derocles, Stéphane A.P.
Derocles, Stéphane A.P. in OpenAIRELunt, David H.;
Kimball, Bruce A.; +1 AuthorsLunt, David H.
Lunt, David H. in OpenAIREBerthe, Sophie C.F.;Derocles, Stéphane A.P.;
Derocles, Stéphane A.P.
Derocles, Stéphane A.P. in OpenAIRELunt, David H.;
Kimball, Bruce A.;Lunt, David H.
Lunt, David H. in OpenAIREEvans, Darren M.;
Evans, Darren M.
Evans, Darren M. in OpenAIREAbstract Simulated climate-warming experiments have provided important insights into the response of terrestrial ecosystems, but few have examined the impacts on agricultural insects, particularly those associated with the ecosystem service of biological pest control. Within a spring-sown wheat crop, we artificially increased temperature by 2 °C and precipitation by 10% in a short-term (April to August 2013) replicated open-field experiment and examined the impacts on coleopteran (mainly Carabidae) diversity and ‘activity-densities’. Diversity indices decreased as a result of warming but were not affected by extra precipitation. We found a significant increase in activity-densities of the four most trapped species due to warming, which was responsible for observed changes in diversity. However, Staphylinidae beetles were negatively affected by the warming treatments while other, less common species were not affected. We provide the first experimental evidence of climate-driven impacts on an important farmland insect community. We discuss the implications of our results in the context of biological control and top-down effects across trophic levels.
Agriculture Ecosyste... arrow_drop_down Agriculture Ecosystems & EnvironmentArticle . 2015 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefUniversity of Hull: Repository@HullArticle . 2015Data sources: Bielefeld Academic Search Engine (BASE)Newcastle University Library ePrints ServiceArticleData sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eu16 citations 16 popularity Average influence Average impulse Top 10% Powered by BIP!
more_vert Agriculture Ecosyste... arrow_drop_down Agriculture Ecosystems & EnvironmentArticle . 2015 . Peer-reviewedLicense: Elsevier TDMData sources: CrossrefUniversity of Hull: Repository@HullArticle . 2015Data sources: Bielefeld Academic Search Engine (BASE)Newcastle University Library ePrints ServiceArticleData sources: Bielefeld Academic Search Engine (BASE)add ClaimPlease grant OpenAIRE to access and update your ORCID works.This Research product is the result of merged Research products in OpenAIRE.
You have already added works in your ORCID record related to the merged Research product.This Research product is the result of merged Research products in OpenAIRE.
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2000Publisher:Elsevier BV Authors: Cephas T. Musabayane; Ross G. Cooper; Richard James Balment; Pitchika Vignananda Vara Prasada Rao;pmid: 11163120
This study investigated the effects of long-term chloroquine and ethanol administration on renal fluid and electrolyte handling and kidney structure. Male Sprague-Dawley rats were orally administered with chloroquine diphosphate (20 microg kg(-1) bw) and/or ethanol (1.6 g kg(-1) bw) every third consecutive day for 4 weeks. Urine volume and total urinary outputs of Na+ and K+ were determined from 24-h samples. For detailed renal studies, rats were subsequently anaesthetised and challenged with a continuous jugular infusion of 0.077 M NaCl at 150 microl min(-1) 24 h after the last treatment. After a 3-h equilibration period, urine flow, Na+ and K+ excretion rates were determined over a 4-h period. Plasma concentrations of AVP and aldosterone were measured in unanaesthetised rats and in anaesthetised rats after hypotonic saline infusion. In separate groups, the rats were anaesthetised with an overdose of ether after 4 weeks of treatment and part of the right kidney was quickly collected and routinely processed for light microscopy. Chloroquine decreased Na+ excretion and increased plasma aldosterone concentrations in anaesthetised rats. Ethanol alone did not alter urinary Na+ outputs or aldosterone levels. Combined chloroquine and ethanol increased renal Na+ excretion, but did not affect plasma aldosterone levels. In unanaesthetised animals all treatments increased aldosterone levels by comparison with control rats. Urinary Na+ excretion was decreased by separate administration of either chloroquine or ethanol, but increased by combined treatment. Microscopic studies showed that concurrent chloroquine and ethanol administration induced extensive damage of the proximal tubule and collecting ducts cells. The results of this study suggest that alcohol consumption and chloroquine administration could result in diminished renal function possibly due to alteration of renally active hormones or kidney morphology.
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For further information contact us at helpdesk@openaire.eu14 citations 14 popularity Average influence Average impulse Average Powered by BIP!
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For further information contact us at helpdesk@openaire.eudescription Publicationkeyboard_double_arrow_right Article , Journal 2016Publisher:Elsevier BV Authors: ChunYan Zhang;XiaoJun Su;
XingYao Xiong; QiuLong Hu; +3 AuthorsXiaoJun Su
XiaoJun Su in OpenAIREChunYan Zhang;XiaoJun Su;
XingYao Xiong; QiuLong Hu; Samuel Amartey; XingHe Tan; Wensheng Qin;XiaoJun Su
XiaoJun Su in OpenAIREAbstract We investigated changes in the physical and chemical properties of rapeseed straw after treatment with different doses of 60 Co γ-irradiation (0 kGy-1200 kGy). Raman spectra, electron spin resonance (ESR), and nuclear magnetic resonance (NMR) analyses of the pretreated samples showed that the irradiation partially destroyed the intra- or intermolecular structure of rapeseed straw. Particle size distribution and specific surface area analyses suggested that irradiation decreased the particle size, narrowed the distribution range, and increased the specific surface area. Thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC) curves showed that increasing the irradiated dose decreased the thermal stability of the treated rapeseed straw and increased the reactivity. Elemental analyses suggested that the oxygen content slightly increased, suggesting that oxygen in the air may be involved in the reaction. These results demonstrate that γ-irradiation can induce a series of changes in the physical and chemical properties of rapeseed straw.
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For further information contact us at helpdesk@openaire.eu22 citations 22 popularity Top 10% influence Average impulse Top 10% Powered by BIP!
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