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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Barrak Alahmad; Haitham Khraishah; Dominic Royé; Ana Monteiro; +42 Authors

    Background: Cardiovascular disease is the leading cause of death worldwide. Existing studies on the association between temperatures and cardiovascular deaths have been limited in geographic zones and have generally considered associations with total cardiovascular deaths rather than cause-specific cardiovascular deaths. Methods: We used unified data collection protocols within the Multi-Country Multi-City Collaborative Network to assemble a database of daily counts of specific cardiovascular causes of death from 567 cities in 27 countries across 5 continents in overlapping periods ranging from 1979 to 2019. City-specific daily ambient temperatures were obtained from weather stations and climate reanalysis models. To investigate cardiovascular mortality associations with extreme hot and cold temperatures, we fit case-crossover models in each city and then used a mixed-effects meta-analytic framework to pool individual city estimates. Extreme temperature percentiles were compared with the minimum mortality temperature in each location. Excess deaths were calculated for a range of extreme temperature days. Results: The analyses included deaths from any cardiovascular cause (32 154 935), ischemic heart disease (11 745 880), stroke (9 351 312), heart failure (3 673 723), and arrhythmia (670 859). At extreme temperature percentiles, heat (99th percentile) and cold (1st percentile) were associated with higher risk of dying from any cardiovascular cause, ischemic heart disease, stroke, and heart failure as compared to the minimum mortality temperature, which is the temperature associated with least mortality. Across a range of extreme temperatures, hot days (above 97.5th percentile) and cold days (below 2.5th percentile) accounted for 2.2 (95% empirical CI [eCI], 2.1–2.3) and 9.1 (95% eCI, 8.9–9.2) excess deaths for every 1000 cardiovascular deaths, respectively. Heart failure was associated with the highest excess deaths proportion from extreme hot and cold days with 2.6 (95% eCI, 2.4–2.8) and 12.8 (95% eCI, 12.2–13.1) for every 1000 heart failure deaths, respectively. Conclusions: Across a large, multinational sample, exposure to extreme hot and cold temperatures was associated with a greater risk of mortality from multiple common cardiovascular conditions. The intersections between extreme temperatures and cardiovascular health need to be thoroughly characterized in the present day—and especially under a changing climate.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Bern Open Repository...arrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Circulation
    Article . 2023 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    DIGITAL.CSIC
    Article . 2024 . Peer-reviewed
    Data sources: DIGITAL.CSIC
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    edoc
    Article . 2023 . Peer-reviewed
    Data sources: edoc
    https://dx.doi.org/10.60692/w2...
    Other literature type . 2023
    Data sources: Datacite
    https://dx.doi.org/10.5451/uni...
    Other literature type . 2023
    Data sources: Datacite
    https://dx.doi.org/10.60692/17...
    Other literature type . 2023
    Data sources: Datacite
    Circulation
    Article . 2022
    image/svg+xml Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao Closed Access logo, derived from PLoS Open Access logo. This version with transparent background. http://commons.wikimedia.org/wiki/File:Closed_Access_logo_transparent.svg Jakob Voss, based on art designer at PLoS, modified by Wikipedia users Nina and Beao
    Ktisis
    Article . 2023
    Data sources: Ktisis
    Circulation
    Article . 2023 . Peer-reviewed
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Takahiro Oda; Jun’ya Takakura; Longlong Tang; Toshichika Iizumi; +19 Authors

    Abstract What will be the aggregated cost of climate change in achieving the Paris Agreement, including mitigation, adaptation, and residual impacts? Several studies estimated the aggregated cost but did not always consider the critical issues. Some do not address non-market values such as biodiversity and human health, and most do not address differentiating discount rates. In this study, we estimate the aggregated cost of climate change using an integrated assessment model linked with detailed-process-based climate impact models and different discount rates for market and non-market values. The analysis reveals that a climate policy with minimal aggregated cost is sensitive to socioeconomic scenarios and the way discount rates are applied. The results elucidate that a lower discount rate to non-market value—that is, a higher estimate of future value—makes the aggregated cost of achieving the Paris Agreement economically reasonable.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ IIASA DAREarrow_drop_down
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Environmental Research Letters
    Article . 2023 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Environmental Research Letters
    Article . 2023
    Data sources: DOAJ
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ IIASA DAREarrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Environmental Research Letters
      Article . 2023 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Environmental Research Letters
      Article . 2023
      Data sources: DOAJ
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Kazutaka Oka; Jinyu He; Yasushi Honda; Yasuaki Hijioka;

    Abstract Although the risk of heatstroke is already severe in Japan, it is expected to increase due to climate change. Researchers have mainly focused on future increases in heatstroke morbidity and mortality to project the risk of heatstroke in Japan. However, the economic burden of heatstroke remains unclear. This study evaluated ambulance transport costs for patients with heatstroke as an economic burden. The study area was Tokyo, Japan. Two cases of ambulance transport costs were evaluated: (i) annual ambulance transport costs for patients with heatstroke and (ii) ambulance transport costs for patients with heatstroke during extreme heat events (defined as the daily maximum temperature occurring once every 50 years). We evaluated the ratio of (ii) to (i) to determine the impacts of extreme heat events. Five climate models associated with three greenhouse gas emission scenarios were used for future projections. Future demographic changes were also considered, with the population of ≥ the 65-year age group projected to increase due to Japan’s aging society. In contrast, the population for the 7–17 and 18–64-year age groups was projected to remain the same or decrease. The projection periods were set to the present (1985–2014), mid-21st century (2021–2050), and late 21st century (2071–2100). Present annual ambulance transport costs were estimated to be JPY 145 million. In contrast, those in the mid-and late 21st century were estimated to range from JPY 280–520 million, except under SSP5-RCP8.5 in the late 21st century, for which a significant increase was projected. Furthermore, one of the climate scenarios for the mid-21st century yielded a ratio of (ii) to (i) of ∼100%, indicating that a single extreme heat event could substantially increase the annual ambulance transport costs. These results suggest that efforts to reduce the unnecessary use of ambulances are essential to limit the future economic burden.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Environmental Resear...arrow_drop_down
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    Environmental Research Communications
    Article . 2025 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Environmental Resear...arrow_drop_down
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      Environmental Research Communications
      Article . 2025 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Zhou, Lu; Schneider, Alexandra; Kim, Ho; Zhang, Yuqiang; +9 Authors

    BACKGROUND: The health impacts of climate warming are usually quantified based on daily average temperatures. However, extra health risks might result from hot nights. We project the future mortality burden due to hot nights. METHODS: We selected the hot night excess (HNE) to represent the intensity of night-time heat, which was calculated as the excess sum of high temperature during night time. We collected historical mortality data in 28 cities from three east Asian countries, from 1981 to 2010. The associations between HNE and mortality in each city were firstly examined using a generalised additive model in combination with a distributed lag non-linear model over lag 0-10 days. We then pooled the cumulative associations using a univariate meta-regression model at the national or regional levels. Historical and future hourly temperature series were projected under two scenarios of greenhouse-gas emissions from 1980-2099, with ten general circulation models. We then projected the attributable fraction of mortality due to HNE under each scenario. FINDINGS: Our dataset comprised 28 cities across three countries (Japan, South Korea, and China), including 9 185 598 deaths. The time-series analyses showed the HNE was significantly associated with increased mortality risks, the relative mortality risk on days with hot nights could be 50% higher than on days with non-hot nights. Compared with the rise in daily mean temperature (lower than 20%), the frequency of hot nights would increase more than 30% and the intensity of hot night would increase by 50% by 2100s. The attributable fraction of mortality due to hot nights was projected to be 3·68% (95% CI 1·20 to 6·17) under a strict emission control scenario (SSP126). Under a medium emission control scenario (SSP245), the attributable fraction of mortality was projected to increase up to 5·79% (2·07 to 9·52), which is 0·95% (-0·39 to 2·29) more than the attributable fraction of mortality due to daily mean temperature. INTERPRETATION: Our study provides evidence for significant mortality risks and burden in association with night-time warming across Japan, South Korea, and China. Our findings suggest a growing role of night-time warming in heat-related health effects in a changing climate. FUNDING: The National Natural Science Foundation of China, Shanghai International Science and Technology Partnership Project.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ The Lancet Planetary...arrow_drop_down
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    The Lancet Planetary Health
    Article . 2022 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    UNC Dataverse
    Article . 2022
    Data sources: Datacite
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      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ The Lancet Planetary...arrow_drop_down
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      The Lancet Planetary Health
      Article . 2022 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
      UNC Dataverse
      Article . 2022
      Data sources: Datacite
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Kai Chen; Evan de Schrijver; Sidharth Sivaraj; Francesco Sera; +70 Authors

    AbstractOlder adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on these trends remains unclear. Here we show that at 1.5 °C, 2 °C, and 3 °C of global warming, heat-related mortality in 800 locations across 50 countries/areas will increase by 0.5%, 1.0%, and 2.5%, respectively; among which 1 in 5 to 1 in 4 heat-related deaths can be attributed to population aging. Despite a projected decrease in cold-related mortality due to progressive warming alone, population aging will mostly counteract this trend, leading to a net increase in cold-related mortality by 0.1%–0.4% at 1.5–3 °C global warming. Our findings indicate that population aging constitutes a crucial driver for future heat- and cold-related deaths, with increasing mortality burden for both heat and cold due to the aging population.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Bern Open Repository...arrow_drop_down
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    Authors: Yao Wu; Shanshan Li; Qi Zhao; Bo Wen; +63 Authors

    L'augmentation du risque de mortalité est associée à une variabilité de la température à court terme. Cependant, à notre connaissance, il n'y a pas eu d'évaluation complète de la charge de mortalité liée à la variabilité de la température dans le monde. Dans cette étude, en utilisant les données du MCC Collaborative Research Network, nous avons d'abord exploré l'association entre la variabilité de la température et la mortalité dans 43 pays ou régions. Ensuite, pour fournir une image plus complète de la charge mondiale de mortalité associée à la variabilité de la température, des données de température maillées mondiales avec une résolution de 0,5° ×0,5° ont été utilisées pour évaluer la charge de mortalité liée à la variabilité de la température aux niveaux mondial, régional et national. En outre, les tendances temporelles de la charge de mortalité liée à la variabilité de la température ont également été explorées à partir de 2000-19. Dans cette étude de modélisation, nous avons appliqué une approche méta-analytique en trois étapes pour évaluer la charge de mortalité liée à la variabilité de la température mondiale à une résolution spatiale de 0,5° ×0,5° à partir de 2000-19. La variabilité de la température a été calculée comme l'écart-type de la moyenne des températures minimales et maximales des mêmes jours et des jours précédents. Nous avons d'abord obtenu des associations de mortalité liées à la variabilité de la température spécifiques à l'emplacement sur la base d'une série temporelle quotidienne de 750 emplacements du Multi-country Multi-city Collaborative Research Network. Nous avons ensuite construit un modèle de méta-régression multivariable avec cinq prédicteurs pour estimer les associations de mortalité liées à la variabilité de la température spécifique à la grille à travers le monde. Enfin, le pourcentage d'excès de mortalité et le taux de surmortalité ont été calculés pour quantifier la charge de mortalité liée à la variabilité de la température et pour explorer davantage sa tendance temporelle sur deux décennies. Une tendance croissante de la variabilité de la température a été identifiée au niveau mondial de 2000 à 2019. À l'échelle mondiale, 1 753 392 décès (IC à 95 % 1 159 901-2 357 718) ont été associés à la variabilité de la température par an, représentant 3·4 % (2·2-4·6) de tous les décès. La plupart de l'Asie, de l'Australie et de la Nouvelle-Zélande présentaient un pourcentage de surmortalité plus élevé que la moyenne mondiale. À l'échelle mondiale, le pourcentage d'excès de mortalité a augmenté d'environ 4·6 % (3·7-5·3) par décennie. La plus forte augmentation s'est produite en Australie et en Nouvelle-Zélande (7,3 %, ICà 95 % 4,3-10,4), suivie de l'Europe (4,4 %, 2,2-5,6) et de l'Afrique (3,3,1,9-4,6). Globalement, une charge de mortalité substantielle a été associée à la variabilité de la température, montrant une hétérogénéité géographique et une tendance temporelle légèrement croissante. Nos résultats pourraient aider à sensibiliser le public et à améliorer la compréhension des impacts sur la santé de la variabilité de la température.Australian Research Council, Australian National Health & Medical Research Council. El aumento del riesgo de mortalidad se asocia con la variabilidad de la temperatura a corto plazo. Sin embargo, hasta donde sabemos, no ha habido una evaluación exhaustiva de la carga de mortalidad relacionada con la variabilidad de la temperatura en todo el mundo. En este estudio, utilizando datos de la Red de Investigación Colaborativa de MCC, primero exploramos la asociación entre la variabilidad de la temperatura y la mortalidad en 43 países o regiones. Luego, para proporcionar una imagen más completa de la carga global de mortalidad asociada con la variabilidad de la temperatura, se utilizaron datos de temperatura cuadriculados globales con una resolución de 0·5° × 0·5° para evaluar la carga de mortalidad relacionada con la variabilidad de la temperatura a nivel mundial, regional y nacional. Además, también se exploraron las tendencias temporales en la carga de mortalidad relacionada con la variabilidad de la temperatura desde 2000-19. En este estudio de modelado, aplicamos un enfoque metaanalítico de tres etapas para evaluar la carga de mortalidad relacionada con la variabilidad de la temperatura global a una resolución espacial de 0·5° × 0·5° desde 2000-19. La variabilidad de temperatura se calculó como la DE de la media de las temperaturas mínimas y máximas del mismo día y de los días anteriores. Primero obtuvimos asociaciones de mortalidad relacionadas con la variabilidad de temperatura específicas de la ubicación basadas en una serie temporal diaria de 750 ubicaciones de la Red de Investigación Colaborativa Multinacional y Multinacional. Posteriormente, construimos un modelo de metarregresión multivariable con cinco predictores para estimar las asociaciones de mortalidad relacionadas con la variabilidad de temperatura específicas de la cuadrícula en todo el mundo. Finalmente, se calculó el exceso porcentual de mortalidad y la tasa de mortalidad excesiva para cuantificar la carga de mortalidad relacionada con la variabilidad de la temperatura y para explorar más a fondo su tendencia temporal durante dos décadas. Se identificó una tendencia creciente en la variabilidad de la temperatura a nivel mundial de 2000 a 2019. A nivel mundial, 1 753 392 muertes (IC 95% 1 159 901-2 357 718) se asociaron con la variabilidad de la temperatura por año, lo que representa el 3·4% (2·2-4·6) de todas las muertes. Se observó que la mayor parte de Asia, Australia y Nueva Zelanda tenían un exceso porcentual de mortalidad mayor que la media mundial. A nivel mundial, el porcentaje de exceso de mortalidad aumentó en aproximadamente un 4,6% (3,7-5,3) por década. El mayor aumento se produjo en Australia y Nueva Zelanda (7·3%, IC 95% 4·3-10·4), seguido de Europa (4·4%, 2 · 2-5·6) y África (3·3, 1 · 9-4·6). A nivel mundial, una carga de mortalidad sustancial se asoció con la variabilidad de la temperatura, mostrando heterogeneidad geográfica y una tendencia temporal ligeramente creciente. Nuestros hallazgos podrían ayudar a aumentar la conciencia pública y mejorar la comprensión de los impactos en la salud de la variabilidad de la temperatura. Consejo Australiano de Investigación, Consejo Nacional Australiano de Investigación Médica y de Salud. Increased mortality risk is associated with short-term temperature variability. However, to our knowledge, there has been no comprehensive assessment of the temperature variability-related mortality burden worldwide. In this study, using data from the MCC Collaborative Research Network, we first explored the association between temperature variability and mortality across 43 countries or regions. Then, to provide a more comprehensive picture of the global burden of mortality associated with temperature variability, global gridded temperature data with a resolution of 0·5° × 0·5° were used to assess the temperature variability-related mortality burden at the global, regional, and national levels. Furthermore, temporal trends in temperature variability-related mortality burden were also explored from 2000-19.In this modelling study, we applied a three-stage meta-analytical approach to assess the global temperature variability-related mortality burden at a spatial resolution of 0·5° × 0·5° from 2000-19. Temperature variability was calculated as the SD of the average of the same and previous days' minimum and maximum temperatures. We first obtained location-specific temperature variability related-mortality associations based on a daily time series of 750 locations from the Multi-country Multi-city Collaborative Research Network. We subsequently constructed a multivariable meta-regression model with five predictors to estimate grid-specific temperature variability related-mortality associations across the globe. Finally, percentage excess in mortality and excess mortality rate were calculated to quantify the temperature variability-related mortality burden and to further explore its temporal trend over two decades.An increasing trend in temperature variability was identified at the global level from 2000 to 2019. Globally, 1 753 392 deaths (95% CI 1 159 901-2 357 718) were associated with temperature variability per year, accounting for 3·4% (2·2-4·6) of all deaths. Most of Asia, Australia, and New Zealand were observed to have a higher percentage excess in mortality than the global mean. Globally, the percentage excess in mortality increased by about 4·6% (3·7-5·3) per decade. The largest increase occurred in Australia and New Zealand (7·3%, 95% CI 4·3-10·4), followed by Europe (4·4%, 2·2-5·6) and Africa (3·3, 1·9-4·6).Globally, a substantial mortality burden was associated with temperature variability, showing geographical heterogeneity and a slightly increasing temporal trend. Our findings could assist in raising public awareness and improving the understanding of the health impacts of temperature variability.Australian Research Council, Australian National Health & Medical Research Council. ترتبط زيادة خطر الوفاة بتقلب درجة الحرارة على المدى القصير. ومع ذلك، على حد علمنا، لم يكن هناك تقييم شامل لعبء الوفيات المرتبطة بتقلب درجة الحرارة في جميع أنحاء العالم. في هذه الدراسة، باستخدام بيانات من شبكة البحوث التعاونية لمؤسسة تحدي الألفية، استكشفنا أولاً العلاقة بين تقلب درجة الحرارة والوفيات عبر 43 دولة أو منطقة. بعد ذلك، لتوفير صورة أكثر شمولاً للعبء العالمي للوفيات المرتبطة بتقلب درجة الحرارة، تم استخدام بيانات درجة الحرارة العالمية الشبكية بدقة 0·5° × 0·5° لتقييم عبء الوفيات المرتبط بتقلب درجة الحرارة على المستويات العالمية والإقليمية والوطنية. علاوة على ذلك، تم أيضًا استكشاف الاتجاهات الزمنية في عبء الوفيات المرتبط بتقلب درجة الحرارة من 2000-19. في دراسة النمذجة هذه، طبقنا نهجًا تحليليًا تلويًا من ثلاث مراحل لتقييم عبء الوفيات المرتبط بتقلب درجة الحرارة العالمية بدقة مكانية قدرها 0·5° × 0·5° من 2000-19. تم حساب تقلب درجة الحرارة على أنه SD لمتوسط نفس درجات الحرارة الدنيا والقصوى للأيام السابقة. حصلنا أولاً على ارتباطات الوفيات المرتبطة بتقلبات درجات الحرارة الخاصة بالموقع بناءً على سلسلة زمنية يومية تضم 750 موقعًا من شبكة الأبحاث التعاونية متعددة المدن. قمنا بعد ذلك ببناء نموذج ميتا انحدار متعدد المتغيرات مع خمسة تنبؤات لتقدير التقلبات في درجات الحرارة الخاصة بالشبكة والارتباطات المرتبطة بالوفيات في جميع أنحاء العالم. أخيرًا، تم حساب النسبة المئوية للزيادة في معدل الوفيات ومعدل الوفيات الزائد لتحديد عبء الوفيات المرتبط بتقلب درجة الحرارة ولمواصلة استكشاف اتجاهه الزمني على مدى عقدين من الزمن. تم تحديد اتجاه متزايد في تقلب درجة الحرارة على المستوى العالمي من عام 2000 إلى عام 2019. على الصعيد العالمي، ارتبطت 1،753،392 حالة وفاة (95 ٪ CI 1،159،901-2،357،718) بتقلب درجة الحرارة سنويًا، وهو ما يمثل 3·4 ٪ (2·2-4·6) من جميع الوفيات. ولوحظ أن معظم آسيا وأستراليا ونيوزيلندا لديها نسبة مئوية أعلى من الزيادة في الوفيات من المتوسط العالمي. على الصعيد العالمي، زادت النسبة المئوية للزيادة في الوفيات بنحو 4.6٪(3.7-5.3) لكل عقد. حدثت أكبر زيادة في أستراليا ونيوزيلندا (7·3 ٪، 95 ٪ CI 4·3-10·4)، تليها أوروبا (4· 4 ٪، 2·2-5·6) وأفريقيا (3·3، 1 · 9-4·6). على الصعيد العالمي، ارتبط عبء الوفيات الكبير بتقلب درجة الحرارة، مما يدل على عدم التجانس الجغرافي والاتجاه الزمني المتزايد قليلاً. يمكن أن تساعد النتائج التي توصلنا إليها في زيادة الوعي العام وتحسين فهم الآثار الصحية لتقلب درجة الحرارة. مجلس البحوث الأسترالي، المجلس الوطني الأسترالي للبحوث الصحية والطبية.

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    The Lancet Planetary Health
    Article . 2022 . Peer-reviewed
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    The Lancet Planetary Health
    Article . 2022
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    edoc
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    The Lancet Planetary Health
    Article . 2022 . Peer-reviewed
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    http://dx.doi.org/10.1016/s254...
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      The Lancet Planetary Health
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      The Lancet Planetary Health
      Article . 2022
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      edoc
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      The Lancet Planetary Health
      Article . 2022 . Peer-reviewed
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      http://dx.doi.org/10.1016/s254...
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      https://dx.doi.org/10.60692/vg...
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      Digital.CSIC
      Article . 2022 . Peer-reviewed
      Data sources: Digital.CSIC
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Vera Ling Hui Phung; Kazutaka Oka; Yasushi Honda; Yasuaki Hijioka; +5 Authors

    Le changement climatique et ses effets ultérieurs sur la température ont soulevé des préoccupations en matière de santé publique mondiale. Bien que de nombreuses études épidémiologiques aient montré les effets néfastes de la température sur la santé, l'association reste incertaine pour les enfants de moins de cinq ans et ceux des régions climatiques tropicales. Nous avons mené une étude de cas croisée stratifiée dans le temps en deux étapes pour examiner l'association entre la température et la mortalité des moins de cinq ans, couvrant la période de 2014 à 2018 dans les six régions de Malaisie. Dans la première étape, nous avons estimé les associations température-mortalité spécifiques à la région en utilisant une régression de Poisson conditionnelle et des modèles non linéaires de décalage distribués. Nous avons utilisé un modèle de méta-régression multivarié pour regrouper les estimations spécifiques à la région et examiner le rôle potentiel des caractéristiques locales dans l'association, qui comprend des informations géographiques, des données démographiques, le statut socio-économique, des mesures de température à long terme et l'accès aux soins de santé par région. La température en Malaisie variait de 22 °C à 31 °C, avec une moyenne de 27,6 °C. Aucune saisonnalité claire n'a été observée dans la mortalité des moins de cinq ans. Nous n'avons trouvé aucune preuve solide de l'association entre la température et la mortalité des moins de cinq ans, avec une courbe exposition-réponse en forme de « M ». La température minimale de mortalité (MMT) a été identifiée à 27,1 °C. Parmi plusieurs caractéristiques locales, seuls le niveau d'éducation et les taux de lits d'hôpital ont réduit l'hétérogénéité résiduelle dans l'association. Cependant, la modification de l'effet par ces variables n'était pas significative. Cette étude suggère une association nulle entre la température et la mortalité des moins de cinq ans en Malaisie, qui a un climat tropical. Le motif en forme de « M- » suggère que les moins de cinq ans peuvent être vulnérables aux changements de température, même avec un petit changement de température par rapport au MMT. Cependant, les faibles risques avec une grande incertitude aux températures extrêmes sont restés peu concluants. Les rôles potentiels du niveau d'éducation et du taux de lits d'hôpital étaient statistiquement non concluants. El cambio climático y sus efectos posteriores sobre la temperatura han planteado problemas de salud pública a nivel mundial. Aunque numerosos estudios epidemiológicos han demostrado los efectos adversos de la temperatura para la salud, la asociación sigue sin estar clara para los niños menores de cinco años y los de las regiones de clima tropical. Realizamos un estudio cruzado de casos estratificado en dos etapas para examinar la asociación entre la temperatura y la mortalidad de menores de cinco años, que abarca el período de 2014 a 2018 en las seis regiones de Malasia. En la primera etapa, estimamos las asociaciones de temperatura-mortalidad específicas de la región utilizando una regresión condicional de Poisson y modelos no lineales de retardo distribuido. Utilizamos un modelo de metarregresión multivariante para agrupar las estimaciones específicas de la región y examinar el papel potencial de las características locales en la asociación, que incluye información geográfica, demografía, estado socioeconómico, métricas de temperatura a largo plazo y acceso a la atención médica por región. La temperatura en Malasia osciló entre 22 °C y 31 °C, con una media de 27,6 °C. No se observó una estacionalidad clara en la mortalidad de menores de cinco años. No encontramos pruebas sólidas de la asociación entre la temperatura y la mortalidad de menores de cinco años, con una curva de exposición-respuesta en forma de "M". La temperatura mínima de mortalidad (TMM) se identificó en 27,1 °C. Entre varias características locales, solo el nivel educativo y las tasas de camas hospitalarias redujeron la heterogeneidad residual en la asociación. Sin embargo, la modificación del efecto por estas variables no fue significativa. Este estudio sugiere una asociación nula entre la temperatura y la mortalidad de menores de cinco años en Malasia, que tiene un clima tropical. El patrón en forma de "M" sugiere que los menores de cinco años pueden ser vulnerables a los cambios de temperatura, incluso con un pequeño cambio de temperatura en referencia a la TMM. Sin embargo, los riesgos débiles con una gran incertidumbre a temperaturas extremas no fueron concluyentes. Los posibles roles del nivel educativo y la tasa de camas hospitalarias no fueron estadísticamente concluyentes. Climate change and its subsequent effects on temperature have raised global public health concerns. Although numerous epidemiological studies have shown the adverse health effects of temperature, the association remains unclear for children aged below five years old and those in tropical climate regions.We conducted a two-stage time-stratified case-crossover study to examine the association between temperature and under-five mortality, spanning the period from 2014 to 2018 across all six regions in Malaysia. In the first stage, we estimated region-specific temperature-mortality associations using a conditional Poisson regression and distributed lag nonlinear models. We used a multivariate meta-regression model to pool the region-specific estimates and examine the potential role of local characteristics in the association, which includes geographical information, demographics, socioeconomic status, long-term temperature metrics, and healthcare access by region.Temperature in Malaysia ranged from 22 °C to 31 °C, with a mean of 27.6 °C. No clear seasonality was observed in under-five mortality. We found no strong evidence of the association between temperature and under-five mortality, with an "M-" shaped exposure-response curve. The minimum mortality temperature (MMT) was identified at 27.1 °C. Among several local characteristics, only education level and hospital bed rates reduced the residual heterogeneity in the association. However, effect modification by these variables were not significant.This study suggests a null association between temperature and under-five mortality in Malaysia, which has a tropical climate. The "M-" shaped pattern suggests that under-fives may be vulnerable to temperature changes, even with a small temperature change in reference to the MMT. However, the weak risks with a large uncertainty at extreme temperatures remained inconclusive. Potential roles of education level and hospital bed rate were statistically inconclusive. أثار تغير المناخ وآثاره اللاحقة على درجة الحرارة مخاوف بشأن الصحة العامة العالمية. على الرغم من أن العديد من الدراسات الوبائية أظهرت الآثار الصحية الضارة لدرجة الحرارة، إلا أن الارتباط لا يزال غير واضح بالنسبة للأطفال الذين تقل أعمارهم عن خمس سنوات وأولئك الموجودين في المناطق المناخية الاستوائية. أجرينا دراسة حالة متقاطعة على مرحلتين لفحص العلاقة بين درجة الحرارة ووفيات الأطفال دون سن الخامسة، والتي تمتد من عام 2014 إلى عام 2018 في جميع المناطق الست في ماليزيا. في المرحلة الأولى، قمنا بتقدير ارتباطات درجة الحرارة والوفيات الخاصة بالمنطقة باستخدام انحدار بواسون المشروط وتوزيع نماذج التأخر غير الخطية. استخدمنا نموذج الانحدار التلوي متعدد المتغيرات لتجميع التقديرات الخاصة بالمنطقة ودراسة الدور المحتمل للخصائص المحلية في الجمعية، والتي تشمل المعلومات الجغرافية، والتركيبة السكانية، والحالة الاجتماعية والاقتصادية، ومقاييس درجة الحرارة على المدى الطويل، والوصول إلى الرعاية الصحية حسب المنطقة. تراوحت درجة الحرارة في ماليزيا من 22 درجة مئوية إلى 31 درجة مئوية، بمتوسط 27.6 درجة مئوية. لم يلاحظ أي موسمية واضحة في وفيات الأطفال دون سن الخامسة. لم نجد أي دليل قوي على الارتباط بين درجة الحرارة ووفيات الأطفال دون سن الخامسة، مع منحنى استجابة للتعرض على شكل "M". تم تحديد درجة الحرارة الدنيا للوفيات (MMT) عند 27.1 درجة مئوية. من بين العديد من الخصائص المحلية، أدى مستوى التعليم ومعدلات الأسرة في المستشفى فقط إلى تقليل عدم التجانس المتبقي في الجمعية. ومع ذلك، لم يكن تعديل التأثير من خلال هذه المتغيرات مهمًا. تشير هذه الدراسة إلى وجود ارتباط فارغ بين درجة الحرارة ووفيات الأطفال دون سن الخامسة في ماليزيا، التي تتمتع بمناخ استوائي. يشير النمط على شكل "M -" إلى أن الأطفال دون سن الخامسة قد يكونون عرضة لتغيرات درجة الحرارة، حتى مع تغير طفيف في درجة الحرارة في إشارة إلى MMT. ومع ذلك، ظلت المخاطر الضعيفة مع عدم اليقين الكبير في درجات الحرارة القصوى غير حاسمة. كانت الأدوار المحتملة لمستوى التعليم ومعدل سرير المستشفى غير حاسمة إحصائيًا.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ Environmental Resear...arrow_drop_down
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    Environmental Research
    Article . 2023 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    https://dx.doi.org/10.60692/mq...
    Other literature type . 2023
    Data sources: Datacite
    https://dx.doi.org/10.60692/fc...
    Other literature type . 2023
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      Environmental Research
      Article . 2023 . Peer-reviewed
      License: CC BY
      Data sources: Crossref
      https://dx.doi.org/10.60692/mq...
      Other literature type . 2023
      Data sources: Datacite
      https://dx.doi.org/10.60692/fc...
      Other literature type . 2023
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Kazutaka Oka; Yasushi Honda; Vera Ling Hui Phung; Yasuaki Hijioka;

    One of the negative consequences of increased air temperatures due to global warming is the associated increase in heat-related mortality and morbidity. Studies that focused on future predictions of heat-related morbidity do not consider the effect of long-term heat adaptation measures, nor do they use evidence-based methods. Therefore, this study aimed to predict the future heatstroke cases for all 47 prefectures of Japan, by considering long-term heat adaptation by translating current geographical differences in heat adaptation to future temporal heat adaptation. Predictions were conducted for age groups of 7-17, 18-64, and ≥65 years. The prediction period was set to a base period (1981-2000), mid-21st century (2031-2050), and the end of the 21st century (2081-2100). We found that the average heatstroke incidence (number of patients with heatstroke transported by ambulance per population) in Japan under five representative climate models and three greenhouse gas (GHG) emissions scenarios increased by 2.92- for 7-17 years, 3.66- for 18-64 years, and 3.26-fold for ≥65 years at the end of the 21st century without heat adaptation. The corresponding numbers were 1.57 for 7-17 years, 1.77 for 18-64 years, and 1.69 for ≥65 years with heat adaptation. Furthermore, the average number of patients with heatstroke transported by ambulance (NPHTA) under all climate models and GHG emissions scenarios increased by 1.02- for 7-17 years, 1.76- for 18-64 years, and 5.50-fold for ≥65 years at the end of 21st century without heat adaptation, where demographic changes were considered. The corresponding numbers were 0.55 for 7-17 years, 0.82 for 18-64 years, and 2.74 for ≥65 years with heat adaptation. The heatstroke incidence, as well as the NPHTA, substantially decreased when heat adaptation was considered. Our method could be applicable to other regions across the globe.

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    Environmental Research
    Article . 2023 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
    https://doi.org/10.2139/ssrn.4...
    Article . 2023 . Peer-reviewed
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      Environmental Research
      Article . 2023 . Peer-reviewed
      License: CC BY
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      https://doi.org/10.2139/ssrn.4...
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Takahiro Oyama; Jun’ya Takakura; Yuri Hosokawa; Yasushi Honda; +3 Authors

    Abstract Millions of students in Japan participate in school sports club activities, where thousands of heat illness cases occur every year. With future climate change, there is concern about the increased health risks posed to students in sports club activities by the worsening heat environment. However, few studies have quantitatively assessed the heat illness risks associated with school sports activities and the effectiveness of countermeasures under future climate change scenarios. Here, we evaluated the impact of heat and effectiveness of countermeasures based on hourly wet-bulb globe temperature (WBGT) projections under multiple climate scenarios. For the 2060s to 2080s, even under a stringent greenhouse gas (GHG) emission control scenario (SSP1-1.9), strenuous exercise will be restricted for one to four months in five out of eight WBGT zones defined for Japan and for one to six months in six zones under the scenario with little control of GHG emissions (SSP5-8.5). In all four scenarios, unlike in the past, all physical activity should be stopped at least once a week in one or more zones. While common countermeasures like early morning exercise and reducing outdoor activity frequency effectively reduce heat illness risks, under the most pessimistic scenario (SSP5-8.5), strenuous exercise would still need to be restricted for one to four months in warmer zones, even with these measures. Common heat illness countermeasures remain necessary for sports club activities at present. However, further measures—such as replacing outdoor activities with indoor sessions—and behavioral changes—such as moving tournaments concentrated during summer vacation to cooler times of the year—will be inevitable as global warming progresses.

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    Environmental Research Health
    Article . 2025 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
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    https://doi.org/10.21203/rs.3....
    Article . 2024 . Peer-reviewed
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    Environmental Research Health
    Article . 2025
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      Environmental Research Health
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      https://doi.org/10.21203/rs.3....
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      Environmental Research Health
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9 Research products
  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Barrak Alahmad; Haitham Khraishah; Dominic Royé; Ana Monteiro; +42 Authors

    Background: Cardiovascular disease is the leading cause of death worldwide. Existing studies on the association between temperatures and cardiovascular deaths have been limited in geographic zones and have generally considered associations with total cardiovascular deaths rather than cause-specific cardiovascular deaths. Methods: We used unified data collection protocols within the Multi-Country Multi-City Collaborative Network to assemble a database of daily counts of specific cardiovascular causes of death from 567 cities in 27 countries across 5 continents in overlapping periods ranging from 1979 to 2019. City-specific daily ambient temperatures were obtained from weather stations and climate reanalysis models. To investigate cardiovascular mortality associations with extreme hot and cold temperatures, we fit case-crossover models in each city and then used a mixed-effects meta-analytic framework to pool individual city estimates. Extreme temperature percentiles were compared with the minimum mortality temperature in each location. Excess deaths were calculated for a range of extreme temperature days. Results: The analyses included deaths from any cardiovascular cause (32 154 935), ischemic heart disease (11 745 880), stroke (9 351 312), heart failure (3 673 723), and arrhythmia (670 859). At extreme temperature percentiles, heat (99th percentile) and cold (1st percentile) were associated with higher risk of dying from any cardiovascular cause, ischemic heart disease, stroke, and heart failure as compared to the minimum mortality temperature, which is the temperature associated with least mortality. Across a range of extreme temperatures, hot days (above 97.5th percentile) and cold days (below 2.5th percentile) accounted for 2.2 (95% empirical CI [eCI], 2.1–2.3) and 9.1 (95% eCI, 8.9–9.2) excess deaths for every 1000 cardiovascular deaths, respectively. Heart failure was associated with the highest excess deaths proportion from extreme hot and cold days with 2.6 (95% eCI, 2.4–2.8) and 12.8 (95% eCI, 12.2–13.1) for every 1000 heart failure deaths, respectively. Conclusions: Across a large, multinational sample, exposure to extreme hot and cold temperatures was associated with a greater risk of mortality from multiple common cardiovascular conditions. The intersections between extreme temperatures and cardiovascular health need to be thoroughly characterized in the present day—and especially under a changing climate.

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    Circulation
    Article . 2023 . Peer-reviewed
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    DIGITAL.CSIC
    Article . 2024 . Peer-reviewed
    Data sources: DIGITAL.CSIC
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    edoc
    Article . 2023 . Peer-reviewed
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    https://dx.doi.org/10.60692/w2...
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    https://dx.doi.org/10.5451/uni...
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    https://dx.doi.org/10.60692/17...
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    Circulation
    Article . 2022
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    Ktisis
    Article . 2023
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    Article . 2023 . Peer-reviewed
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    Authors: Takahiro Oda; Jun’ya Takakura; Longlong Tang; Toshichika Iizumi; +19 Authors

    Abstract What will be the aggregated cost of climate change in achieving the Paris Agreement, including mitigation, adaptation, and residual impacts? Several studies estimated the aggregated cost but did not always consider the critical issues. Some do not address non-market values such as biodiversity and human health, and most do not address differentiating discount rates. In this study, we estimate the aggregated cost of climate change using an integrated assessment model linked with detailed-process-based climate impact models and different discount rates for market and non-market values. The analysis reveals that a climate policy with minimal aggregated cost is sensitive to socioeconomic scenarios and the way discount rates are applied. The results elucidate that a lower discount rate to non-market value—that is, a higher estimate of future value—makes the aggregated cost of achieving the Paris Agreement economically reasonable.

    image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ IIASA DAREarrow_drop_down
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    Environmental Research Letters
    Article . 2023 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
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    Environmental Research Letters
    Article . 2023
    Data sources: DOAJ
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      Environmental Research Letters
      Article . 2023 . Peer-reviewed
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      Environmental Research Letters
      Article . 2023
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    Authors: Kazutaka Oka; Jinyu He; Yasushi Honda; Yasuaki Hijioka;

    Abstract Although the risk of heatstroke is already severe in Japan, it is expected to increase due to climate change. Researchers have mainly focused on future increases in heatstroke morbidity and mortality to project the risk of heatstroke in Japan. However, the economic burden of heatstroke remains unclear. This study evaluated ambulance transport costs for patients with heatstroke as an economic burden. The study area was Tokyo, Japan. Two cases of ambulance transport costs were evaluated: (i) annual ambulance transport costs for patients with heatstroke and (ii) ambulance transport costs for patients with heatstroke during extreme heat events (defined as the daily maximum temperature occurring once every 50 years). We evaluated the ratio of (ii) to (i) to determine the impacts of extreme heat events. Five climate models associated with three greenhouse gas emission scenarios were used for future projections. Future demographic changes were also considered, with the population of ≥ the 65-year age group projected to increase due to Japan’s aging society. In contrast, the population for the 7–17 and 18–64-year age groups was projected to remain the same or decrease. The projection periods were set to the present (1985–2014), mid-21st century (2021–2050), and late 21st century (2071–2100). Present annual ambulance transport costs were estimated to be JPY 145 million. In contrast, those in the mid-and late 21st century were estimated to range from JPY 280–520 million, except under SSP5-RCP8.5 in the late 21st century, for which a significant increase was projected. Furthermore, one of the climate scenarios for the mid-21st century yielded a ratio of (ii) to (i) of ∼100%, indicating that a single extreme heat event could substantially increase the annual ambulance transport costs. These results suggest that efforts to reduce the unnecessary use of ambulances are essential to limit the future economic burden.

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    Environmental Research Communications
    Article . 2025 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
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      Environmental Research Communications
      Article . 2025 . Peer-reviewed
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    Authors: Zhou, Lu; Schneider, Alexandra; Kim, Ho; Zhang, Yuqiang; +9 Authors

    BACKGROUND: The health impacts of climate warming are usually quantified based on daily average temperatures. However, extra health risks might result from hot nights. We project the future mortality burden due to hot nights. METHODS: We selected the hot night excess (HNE) to represent the intensity of night-time heat, which was calculated as the excess sum of high temperature during night time. We collected historical mortality data in 28 cities from three east Asian countries, from 1981 to 2010. The associations between HNE and mortality in each city were firstly examined using a generalised additive model in combination with a distributed lag non-linear model over lag 0-10 days. We then pooled the cumulative associations using a univariate meta-regression model at the national or regional levels. Historical and future hourly temperature series were projected under two scenarios of greenhouse-gas emissions from 1980-2099, with ten general circulation models. We then projected the attributable fraction of mortality due to HNE under each scenario. FINDINGS: Our dataset comprised 28 cities across three countries (Japan, South Korea, and China), including 9 185 598 deaths. The time-series analyses showed the HNE was significantly associated with increased mortality risks, the relative mortality risk on days with hot nights could be 50% higher than on days with non-hot nights. Compared with the rise in daily mean temperature (lower than 20%), the frequency of hot nights would increase more than 30% and the intensity of hot night would increase by 50% by 2100s. The attributable fraction of mortality due to hot nights was projected to be 3·68% (95% CI 1·20 to 6·17) under a strict emission control scenario (SSP126). Under a medium emission control scenario (SSP245), the attributable fraction of mortality was projected to increase up to 5·79% (2·07 to 9·52), which is 0·95% (-0·39 to 2·29) more than the attributable fraction of mortality due to daily mean temperature. INTERPRETATION: Our study provides evidence for significant mortality risks and burden in association with night-time warming across Japan, South Korea, and China. Our findings suggest a growing role of night-time warming in heat-related health effects in a changing climate. FUNDING: The National Natural Science Foundation of China, Shanghai International Science and Technology Partnership Project.

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    The Lancet Planetary Health
    Article . 2022 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
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    UNC Dataverse
    Article . 2022
    Data sources: Datacite
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      The Lancet Planetary Health
      Article . 2022 . Peer-reviewed
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      UNC Dataverse
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    Authors: Kai Chen; Evan de Schrijver; Sidharth Sivaraj; Francesco Sera; +70 Authors

    AbstractOlder adults are generally amongst the most vulnerable to heat and cold. While temperature-related health impacts are projected to increase with global warming, the influence of population aging on these trends remains unclear. Here we show that at 1.5 °C, 2 °C, and 3 °C of global warming, heat-related mortality in 800 locations across 50 countries/areas will increase by 0.5%, 1.0%, and 2.5%, respectively; among which 1 in 5 to 1 in 4 heat-related deaths can be attributed to population aging. Despite a projected decrease in cold-related mortality due to progressive warming alone, population aging will mostly counteract this trend, leading to a net increase in cold-related mortality by 0.1%–0.4% at 1.5–3 °C global warming. Our findings indicate that population aging constitutes a crucial driver for future heat- and cold-related deaths, with increasing mortality burden for both heat and cold due to the aging population.

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    Nature Communications
    Article . 2024 . Peer-reviewed
    License: CC BY
    Data sources: Crossref
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    PubMed Central
    Other literature type . 2024
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    Authors: Yao Wu; Shanshan Li; Qi Zhao; Bo Wen; +63 Authors

    L'augmentation du risque de mortalité est associée à une variabilité de la température à court terme. Cependant, à notre connaissance, il n'y a pas eu d'évaluation complète de la charge de mortalité liée à la variabilité de la température dans le monde. Dans cette étude, en utilisant les données du MCC Collaborative Research Network, nous avons d'abord exploré l'association entre la variabilité de la température et la mortalité dans 43 pays ou régions. Ensuite, pour fournir une image plus complète de la charge mondiale de mortalité associée à la variabilité de la température, des données de température maillées mondiales avec une résolution de 0,5° ×0,5° ont été utilisées pour évaluer la charge de mortalité liée à la variabilité de la température aux niveaux mondial, régional et national. En outre, les tendances temporelles de la charge de mortalité liée à la variabilité de la température ont également été explorées à partir de 2000-19. Dans cette étude de modélisation, nous avons appliqué une approche méta-analytique en trois étapes pour évaluer la charge de mortalité liée à la variabilité de la température mondiale à une résolution spatiale de 0,5° ×0,5° à partir de 2000-19. La variabilité de la température a été calculée comme l'écart-type de la moyenne des températures minimales et maximales des mêmes jours et des jours précédents. Nous avons d'abord obtenu des associations de mortalité liées à la variabilité de la température spécifiques à l'emplacement sur la base d'une série temporelle quotidienne de 750 emplacements du Multi-country Multi-city Collaborative Research Network. Nous avons ensuite construit un modèle de méta-régression multivariable avec cinq prédicteurs pour estimer les associations de mortalité liées à la variabilité de la température spécifique à la grille à travers le monde. Enfin, le pourcentage d'excès de mortalité et le taux de surmortalité ont été calculés pour quantifier la charge de mortalité liée à la variabilité de la température et pour explorer davantage sa tendance temporelle sur deux décennies. Une tendance croissante de la variabilité de la température a été identifiée au niveau mondial de 2000 à 2019. À l'échelle mondiale, 1 753 392 décès (IC à 95 % 1 159 901-2 357 718) ont été associés à la variabilité de la température par an, représentant 3·4 % (2·2-4·6) de tous les décès. La plupart de l'Asie, de l'Australie et de la Nouvelle-Zélande présentaient un pourcentage de surmortalité plus élevé que la moyenne mondiale. À l'échelle mondiale, le pourcentage d'excès de mortalité a augmenté d'environ 4·6 % (3·7-5·3) par décennie. La plus forte augmentation s'est produite en Australie et en Nouvelle-Zélande (7,3 %, ICà 95 % 4,3-10,4), suivie de l'Europe (4,4 %, 2,2-5,6) et de l'Afrique (3,3,1,9-4,6). Globalement, une charge de mortalité substantielle a été associée à la variabilité de la température, montrant une hétérogénéité géographique et une tendance temporelle légèrement croissante. Nos résultats pourraient aider à sensibiliser le public et à améliorer la compréhension des impacts sur la santé de la variabilité de la température.Australian Research Council, Australian National Health & Medical Research Council. El aumento del riesgo de mortalidad se asocia con la variabilidad de la temperatura a corto plazo. Sin embargo, hasta donde sabemos, no ha habido una evaluación exhaustiva de la carga de mortalidad relacionada con la variabilidad de la temperatura en todo el mundo. En este estudio, utilizando datos de la Red de Investigación Colaborativa de MCC, primero exploramos la asociación entre la variabilidad de la temperatura y la mortalidad en 43 países o regiones. Luego, para proporcionar una imagen más completa de la carga global de mortalidad asociada con la variabilidad de la temperatura, se utilizaron datos de temperatura cuadriculados globales con una resolución de 0·5° × 0·5° para evaluar la carga de mortalidad relacionada con la variabilidad de la temperatura a nivel mundial, regional y nacional. Además, también se exploraron las tendencias temporales en la carga de mortalidad relacionada con la variabilidad de la temperatura desde 2000-19. En este estudio de modelado, aplicamos un enfoque metaanalítico de tres etapas para evaluar la carga de mortalidad relacionada con la variabilidad de la temperatura global a una resolución espacial de 0·5° × 0·5° desde 2000-19. La variabilidad de temperatura se calculó como la DE de la media de las temperaturas mínimas y máximas del mismo día y de los días anteriores. Primero obtuvimos asociaciones de mortalidad relacionadas con la variabilidad de temperatura específicas de la ubicación basadas en una serie temporal diaria de 750 ubicaciones de la Red de Investigación Colaborativa Multinacional y Multinacional. Posteriormente, construimos un modelo de metarregresión multivariable con cinco predictores para estimar las asociaciones de mortalidad relacionadas con la variabilidad de temperatura específicas de la cuadrícula en todo el mundo. Finalmente, se calculó el exceso porcentual de mortalidad y la tasa de mortalidad excesiva para cuantificar la carga de mortalidad relacionada con la variabilidad de la temperatura y para explorar más a fondo su tendencia temporal durante dos décadas. Se identificó una tendencia creciente en la variabilidad de la temperatura a nivel mundial de 2000 a 2019. A nivel mundial, 1 753 392 muertes (IC 95% 1 159 901-2 357 718) se asociaron con la variabilidad de la temperatura por año, lo que representa el 3·4% (2·2-4·6) de todas las muertes. Se observó que la mayor parte de Asia, Australia y Nueva Zelanda tenían un exceso porcentual de mortalidad mayor que la media mundial. A nivel mundial, el porcentaje de exceso de mortalidad aumentó en aproximadamente un 4,6% (3,7-5,3) por década. El mayor aumento se produjo en Australia y Nueva Zelanda (7·3%, IC 95% 4·3-10·4), seguido de Europa (4·4%, 2 · 2-5·6) y África (3·3, 1 · 9-4·6). A nivel mundial, una carga de mortalidad sustancial se asoció con la variabilidad de la temperatura, mostrando heterogeneidad geográfica y una tendencia temporal ligeramente creciente. Nuestros hallazgos podrían ayudar a aumentar la conciencia pública y mejorar la comprensión de los impactos en la salud de la variabilidad de la temperatura. Consejo Australiano de Investigación, Consejo Nacional Australiano de Investigación Médica y de Salud. Increased mortality risk is associated with short-term temperature variability. However, to our knowledge, there has been no comprehensive assessment of the temperature variability-related mortality burden worldwide. In this study, using data from the MCC Collaborative Research Network, we first explored the association between temperature variability and mortality across 43 countries or regions. Then, to provide a more comprehensive picture of the global burden of mortality associated with temperature variability, global gridded temperature data with a resolution of 0·5° × 0·5° were used to assess the temperature variability-related mortality burden at the global, regional, and national levels. Furthermore, temporal trends in temperature variability-related mortality burden were also explored from 2000-19.In this modelling study, we applied a three-stage meta-analytical approach to assess the global temperature variability-related mortality burden at a spatial resolution of 0·5° × 0·5° from 2000-19. Temperature variability was calculated as the SD of the average of the same and previous days' minimum and maximum temperatures. We first obtained location-specific temperature variability related-mortality associations based on a daily time series of 750 locations from the Multi-country Multi-city Collaborative Research Network. We subsequently constructed a multivariable meta-regression model with five predictors to estimate grid-specific temperature variability related-mortality associations across the globe. Finally, percentage excess in mortality and excess mortality rate were calculated to quantify the temperature variability-related mortality burden and to further explore its temporal trend over two decades.An increasing trend in temperature variability was identified at the global level from 2000 to 2019. Globally, 1 753 392 deaths (95% CI 1 159 901-2 357 718) were associated with temperature variability per year, accounting for 3·4% (2·2-4·6) of all deaths. Most of Asia, Australia, and New Zealand were observed to have a higher percentage excess in mortality than the global mean. Globally, the percentage excess in mortality increased by about 4·6% (3·7-5·3) per decade. The largest increase occurred in Australia and New Zealand (7·3%, 95% CI 4·3-10·4), followed by Europe (4·4%, 2·2-5·6) and Africa (3·3, 1·9-4·6).Globally, a substantial mortality burden was associated with temperature variability, showing geographical heterogeneity and a slightly increasing temporal trend. Our findings could assist in raising public awareness and improving the understanding of the health impacts of temperature variability.Australian Research Council, Australian National Health & Medical Research Council. ترتبط زيادة خطر الوفاة بتقلب درجة الحرارة على المدى القصير. ومع ذلك، على حد علمنا، لم يكن هناك تقييم شامل لعبء الوفيات المرتبطة بتقلب درجة الحرارة في جميع أنحاء العالم. في هذه الدراسة، باستخدام بيانات من شبكة البحوث التعاونية لمؤسسة تحدي الألفية، استكشفنا أولاً العلاقة بين تقلب درجة الحرارة والوفيات عبر 43 دولة أو منطقة. بعد ذلك، لتوفير صورة أكثر شمولاً للعبء العالمي للوفيات المرتبطة بتقلب درجة الحرارة، تم استخدام بيانات درجة الحرارة العالمية الشبكية بدقة 0·5° × 0·5° لتقييم عبء الوفيات المرتبط بتقلب درجة الحرارة على المستويات العالمية والإقليمية والوطنية. علاوة على ذلك، تم أيضًا استكشاف الاتجاهات الزمنية في عبء الوفيات المرتبط بتقلب درجة الحرارة من 2000-19. في دراسة النمذجة هذه، طبقنا نهجًا تحليليًا تلويًا من ثلاث مراحل لتقييم عبء الوفيات المرتبط بتقلب درجة الحرارة العالمية بدقة مكانية قدرها 0·5° × 0·5° من 2000-19. تم حساب تقلب درجة الحرارة على أنه SD لمتوسط نفس درجات الحرارة الدنيا والقصوى للأيام السابقة. حصلنا أولاً على ارتباطات الوفيات المرتبطة بتقلبات درجات الحرارة الخاصة بالموقع بناءً على سلسلة زمنية يومية تضم 750 موقعًا من شبكة الأبحاث التعاونية متعددة المدن. قمنا بعد ذلك ببناء نموذج ميتا انحدار متعدد المتغيرات مع خمسة تنبؤات لتقدير التقلبات في درجات الحرارة الخاصة بالشبكة والارتباطات المرتبطة بالوفيات في جميع أنحاء العالم. أخيرًا، تم حساب النسبة المئوية للزيادة في معدل الوفيات ومعدل الوفيات الزائد لتحديد عبء الوفيات المرتبط بتقلب درجة الحرارة ولمواصلة استكشاف اتجاهه الزمني على مدى عقدين من الزمن. تم تحديد اتجاه متزايد في تقلب درجة الحرارة على المستوى العالمي من عام 2000 إلى عام 2019. على الصعيد العالمي، ارتبطت 1،753،392 حالة وفاة (95 ٪ CI 1،159،901-2،357،718) بتقلب درجة الحرارة سنويًا، وهو ما يمثل 3·4 ٪ (2·2-4·6) من جميع الوفيات. ولوحظ أن معظم آسيا وأستراليا ونيوزيلندا لديها نسبة مئوية أعلى من الزيادة في الوفيات من المتوسط العالمي. على الصعيد العالمي، زادت النسبة المئوية للزيادة في الوفيات بنحو 4.6٪(3.7-5.3) لكل عقد. حدثت أكبر زيادة في أستراليا ونيوزيلندا (7·3 ٪، 95 ٪ CI 4·3-10·4)، تليها أوروبا (4· 4 ٪، 2·2-5·6) وأفريقيا (3·3، 1 · 9-4·6). على الصعيد العالمي، ارتبط عبء الوفيات الكبير بتقلب درجة الحرارة، مما يدل على عدم التجانس الجغرافي والاتجاه الزمني المتزايد قليلاً. يمكن أن تساعد النتائج التي توصلنا إليها في زيادة الوعي العام وتحسين فهم الآثار الصحية لتقلب درجة الحرارة. مجلس البحوث الأسترالي، المجلس الوطني الأسترالي للبحوث الصحية والطبية.

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    The Lancet Planetary Health
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    The Lancet Planetary Health
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    The Lancet Planetary Health
    Article . 2022 . Peer-reviewed
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    http://dx.doi.org/10.1016/s254...
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    https://dx.doi.org/10.60692/vg...
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    Digital.CSIC
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      The Lancet Planetary Health
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      The Lancet Planetary Health
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      edoc
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      The Lancet Planetary Health
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      Digital.CSIC
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  • image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
    Authors: Vera Ling Hui Phung; Kazutaka Oka; Yasushi Honda; Yasuaki Hijioka; +5 Authors

    Le changement climatique et ses effets ultérieurs sur la température ont soulevé des préoccupations en matière de santé publique mondiale. Bien que de nombreuses études épidémiologiques aient montré les effets néfastes de la température sur la santé, l'association reste incertaine pour les enfants de moins de cinq ans et ceux des régions climatiques tropicales. Nous avons mené une étude de cas croisée stratifiée dans le temps en deux étapes pour examiner l'association entre la température et la mortalité des moins de cinq ans, couvrant la période de 2014 à 2018 dans les six régions de Malaisie. Dans la première étape, nous avons estimé les associations température-mortalité spécifiques à la région en utilisant une régression de Poisson conditionnelle et des modèles non linéaires de décalage distribués. Nous avons utilisé un modèle de méta-régression multivarié pour regrouper les estimations spécifiques à la région et examiner le rôle potentiel des caractéristiques locales dans l'association, qui comprend des informations géographiques, des données démographiques, le statut socio-économique, des mesures de température à long terme et l'accès aux soins de santé par région. La température en Malaisie variait de 22 °C à 31 °C, avec une moyenne de 27,6 °C. Aucune saisonnalité claire n'a été observée dans la mortalité des moins de cinq ans. Nous n'avons trouvé aucune preuve solide de l'association entre la température et la mortalité des moins de cinq ans, avec une courbe exposition-réponse en forme de « M ». La température minimale de mortalité (MMT) a été identifiée à 27,1 °C. Parmi plusieurs caractéristiques locales, seuls le niveau d'éducation et les taux de lits d'hôpital ont réduit l'hétérogénéité résiduelle dans l'association. Cependant, la modification de l'effet par ces variables n'était pas significative. Cette étude suggère une association nulle entre la température et la mortalité des moins de cinq ans en Malaisie, qui a un climat tropical. Le motif en forme de « M- » suggère que les moins de cinq ans peuvent être vulnérables aux changements de température, même avec un petit changement de température par rapport au MMT. Cependant, les faibles risques avec une grande incertitude aux températures extrêmes sont restés peu concluants. Les rôles potentiels du niveau d'éducation et du taux de lits d'hôpital étaient statistiquement non concluants. El cambio climático y sus efectos posteriores sobre la temperatura han planteado problemas de salud pública a nivel mundial. Aunque numerosos estudios epidemiológicos han demostrado los efectos adversos de la temperatura para la salud, la asociación sigue sin estar clara para los niños menores de cinco años y los de las regiones de clima tropical. Realizamos un estudio cruzado de casos estratificado en dos etapas para examinar la asociación entre la temperatura y la mortalidad de menores de cinco años, que abarca el período de 2014 a 2018 en las seis regiones de Malasia. En la primera etapa, estimamos las asociaciones de temperatura-mortalidad específicas de la región utilizando una regresión condicional de Poisson y modelos no lineales de retardo distribuido. Utilizamos un modelo de metarregresión multivariante para agrupar las estimaciones específicas de la región y examinar el papel potencial de las características locales en la asociación, que incluye información geográfica, demografía, estado socioeconómico, métricas de temperatura a largo plazo y acceso a la atención médica por región. La temperatura en Malasia osciló entre 22 °C y 31 °C, con una media de 27,6 °C. No se observó una estacionalidad clara en la mortalidad de menores de cinco años. No encontramos pruebas sólidas de la asociación entre la temperatura y la mortalidad de menores de cinco años, con una curva de exposición-respuesta en forma de "M". La temperatura mínima de mortalidad (TMM) se identificó en 27,1 °C. Entre varias características locales, solo el nivel educativo y las tasas de camas hospitalarias redujeron la heterogeneidad residual en la asociación. Sin embargo, la modificación del efecto por estas variables no fue significativa. Este estudio sugiere una asociación nula entre la temperatura y la mortalidad de menores de cinco años en Malasia, que tiene un clima tropical. El patrón en forma de "M" sugiere que los menores de cinco años pueden ser vulnerables a los cambios de temperatura, incluso con un pequeño cambio de temperatura en referencia a la TMM. Sin embargo, los riesgos débiles con una gran incertidumbre a temperaturas extremas no fueron concluyentes. Los posibles roles del nivel educativo y la tasa de camas hospitalarias no fueron estadísticamente concluyentes. Climate change and its subsequent effects on temperature have raised global public health concerns. Although numerous epidemiological studies have shown the adverse health effects of temperature, the association remains unclear for children aged below five years old and those in tropical climate regions.We conducted a two-stage time-stratified case-crossover study to examine the association between temperature and under-five mortality, spanning the period from 2014 to 2018 across all six regions in Malaysia. In the first stage, we estimated region-specific temperature-mortality associations using a conditional Poisson regression and distributed lag nonlinear models. We used a multivariate meta-regression model to pool the region-specific estimates and examine the potential role of local characteristics in the association, which includes geographical information, demographics, socioeconomic status, long-term temperature metrics, and healthcare access by region.Temperature in Malaysia ranged from 22 °C to 31 °C, with a mean of 27.6 °C. No clear seasonality was observed in under-five mortality. We found no strong evidence of the association between temperature and under-five mortality, with an "M-" shaped exposure-response curve. The minimum mortality temperature (MMT) was identified at 27.1 °C. Among several local characteristics, only education level and hospital bed rates reduced the residual heterogeneity in the association. However, effect modification by these variables were not significant.This study suggests a null association between temperature and under-five mortality in Malaysia, which has a tropical climate. The "M-" shaped pattern suggests that under-fives may be vulnerable to temperature changes, even with a small temperature change in reference to the MMT. However, the weak risks with a large uncertainty at extreme temperatures remained inconclusive. Potential roles of education level and hospital bed rate were statistically inconclusive. أثار تغير المناخ وآثاره اللاحقة على درجة الحرارة مخاوف بشأن الصحة العامة العالمية. على الرغم من أن العديد من الدراسات الوبائية أظهرت الآثار الصحية الضارة لدرجة الحرارة، إلا أن الارتباط لا يزال غير واضح بالنسبة للأطفال الذين تقل أعمارهم عن خمس سنوات وأولئك الموجودين في المناطق المناخية الاستوائية. أجرينا دراسة حالة متقاطعة على مرحلتين لفحص العلاقة بين درجة الحرارة ووفيات الأطفال دون سن الخامسة، والتي تمتد من عام 2014 إلى عام 2018 في جميع المناطق الست في ماليزيا. في المرحلة الأولى، قمنا بتقدير ارتباطات درجة الحرارة والوفيات الخاصة بالمنطقة باستخدام انحدار بواسون المشروط وتوزيع نماذج التأخر غير الخطية. استخدمنا نموذج الانحدار التلوي متعدد المتغيرات لتجميع التقديرات الخاصة بالمنطقة ودراسة الدور المحتمل للخصائص المحلية في الجمعية، والتي تشمل المعلومات الجغرافية، والتركيبة السكانية، والحالة الاجتماعية والاقتصادية، ومقاييس درجة الحرارة على المدى الطويل، والوصول إلى الرعاية الصحية حسب المنطقة. تراوحت درجة الحرارة في ماليزيا من 22 درجة مئوية إلى 31 درجة مئوية، بمتوسط 27.6 درجة مئوية. لم يلاحظ أي موسمية واضحة في وفيات الأطفال دون سن الخامسة. لم نجد أي دليل قوي على الارتباط بين درجة الحرارة ووفيات الأطفال دون سن الخامسة، مع منحنى استجابة للتعرض على شكل "M". تم تحديد درجة الحرارة الدنيا للوفيات (MMT) عند 27.1 درجة مئوية. من بين العديد من الخصائص المحلية، أدى مستوى التعليم ومعدلات الأسرة في المستشفى فقط إلى تقليل عدم التجانس المتبقي في الجمعية. ومع ذلك، لم يكن تعديل التأثير من خلال هذه المتغيرات مهمًا. تشير هذه الدراسة إلى وجود ارتباط فارغ بين درجة الحرارة ووفيات الأطفال دون سن الخامسة في ماليزيا، التي تتمتع بمناخ استوائي. يشير النمط على شكل "M -" إلى أن الأطفال دون سن الخامسة قد يكونون عرضة لتغيرات درجة الحرارة، حتى مع تغير طفيف في درجة الحرارة في إشارة إلى MMT. ومع ذلك، ظلت المخاطر الضعيفة مع عدم اليقين الكبير في درجات الحرارة القصوى غير حاسمة. كانت الأدوار المحتملة لمستوى التعليم ومعدل سرير المستشفى غير حاسمة إحصائيًا.

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    Environmental Research
    Article . 2023 . Peer-reviewed
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      Environmental Research
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    Authors: Kazutaka Oka; Yasushi Honda; Vera Ling Hui Phung; Yasuaki Hijioka;

    One of the negative consequences of increased air temperatures due to global warming is the associated increase in heat-related mortality and morbidity. Studies that focused on future predictions of heat-related morbidity do not consider the effect of long-term heat adaptation measures, nor do they use evidence-based methods. Therefore, this study aimed to predict the future heatstroke cases for all 47 prefectures of Japan, by considering long-term heat adaptation by translating current geographical differences in heat adaptation to future temporal heat adaptation. Predictions were conducted for age groups of 7-17, 18-64, and ≥65 years. The prediction period was set to a base period (1981-2000), mid-21st century (2031-2050), and the end of the 21st century (2081-2100). We found that the average heatstroke incidence (number of patients with heatstroke transported by ambulance per population) in Japan under five representative climate models and three greenhouse gas (GHG) emissions scenarios increased by 2.92- for 7-17 years, 3.66- for 18-64 years, and 3.26-fold for ≥65 years at the end of the 21st century without heat adaptation. The corresponding numbers were 1.57 for 7-17 years, 1.77 for 18-64 years, and 1.69 for ≥65 years with heat adaptation. Furthermore, the average number of patients with heatstroke transported by ambulance (NPHTA) under all climate models and GHG emissions scenarios increased by 1.02- for 7-17 years, 1.76- for 18-64 years, and 5.50-fold for ≥65 years at the end of 21st century without heat adaptation, where demographic changes were considered. The corresponding numbers were 0.55 for 7-17 years, 0.82 for 18-64 years, and 2.74 for ≥65 years with heat adaptation. The heatstroke incidence, as well as the NPHTA, substantially decreased when heat adaptation was considered. Our method could be applicable to other regions across the globe.

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    Environmental Research
    Article . 2023 . Peer-reviewed
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    https://doi.org/10.2139/ssrn.4...
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      Environmental Research
      Article . 2023 . Peer-reviewed
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    Authors: Takahiro Oyama; Jun’ya Takakura; Yuri Hosokawa; Yasushi Honda; +3 Authors

    Abstract Millions of students in Japan participate in school sports club activities, where thousands of heat illness cases occur every year. With future climate change, there is concern about the increased health risks posed to students in sports club activities by the worsening heat environment. However, few studies have quantitatively assessed the heat illness risks associated with school sports activities and the effectiveness of countermeasures under future climate change scenarios. Here, we evaluated the impact of heat and effectiveness of countermeasures based on hourly wet-bulb globe temperature (WBGT) projections under multiple climate scenarios. For the 2060s to 2080s, even under a stringent greenhouse gas (GHG) emission control scenario (SSP1-1.9), strenuous exercise will be restricted for one to four months in five out of eight WBGT zones defined for Japan and for one to six months in six zones under the scenario with little control of GHG emissions (SSP5-8.5). In all four scenarios, unlike in the past, all physical activity should be stopped at least once a week in one or more zones. While common countermeasures like early morning exercise and reducing outdoor activity frequency effectively reduce heat illness risks, under the most pessimistic scenario (SSP5-8.5), strenuous exercise would still need to be restricted for one to four months in warmer zones, even with these measures. Common heat illness countermeasures remain necessary for sports club activities at present. However, further measures—such as replacing outdoor activities with indoor sessions—and behavioral changes—such as moving tournaments concentrated during summer vacation to cooler times of the year—will be inevitable as global warming progresses.

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    Environmental Research Health
    Article . 2025 . Peer-reviewed
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    https://doi.org/10.21203/rs.3....
    Article . 2024 . Peer-reviewed
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    Environmental Research Health
    Article . 2025
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      Environmental Research Health
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      https://doi.org/10.21203/rs.3....
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