Destanul Aulia The climate change in Indonesia has affected the fishing activity of fisheries in Indonesia, because the activity of fisheries is strongly influenced by climate change. The change in climate in Indonesia led to changes within the pattern of wind speed, current speed, precipitation, sea-surface temperature and wave height. This conditions will affect the income of the fishermen, who are among the poorest Indonesian. In addition to causing loss of income, climate change also threatens the health of this fishing community. In order to understand the community?s perception about climate change and its affect on the spread of tropical disease and the relationship of both, this survey study conducted. The data gathered through the interviewed based questionnaire. The samples are 71 residents of coastal communities subdistrict Tanjung Beringin, District Serdang Bedagai, who previously suffering from tropical diseases (tuberculosis, malaria, dengue and diarrhea). The results of the study shows that most coastal communities within the study area understand climate changes have occurred in their area. They also understand that climate change will cause the development of tropical diseases, they have suffered. The correlation analysis also shows that there is a significant relationship between perceptions about climate change and tropical diseases. Finally this study suggest that the study area urgently need a health promotion effort, so that people in coastal areas can implement the "clean and healthy living behavior", program to avoid the outbreak of a tropical disease in this area