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Animal models of alcoholic liver disease

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Sep 1993Publisher:Elsevier BVJournal:Baillière's Clinical Gastroenterology, volume 7, pages 609-625 (issn: 0950-3528,

Authors: K.J. Simpson; T.J. Peters;

doi: 10.1016/0950-3528(93)90004-c

pmid: 8219402

Animal models of alcoholic liver disease

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Abstract

The development of animal models of human disease greatly enhances our ability to study the pathogenesis, prevention and treatment of a particular disease. With relevance to alcoholic liver disease, the use of animal models allows control of genetic heterogeneity, the route, frequency, amount and type of alcohol consumed, and other variables such as nutritional factors and concomitant viral infection. Many different models have been developed to study the toxic effect of alcohol on a variety of organs, but only those used to study alcoholic liver disease are discussed here in detail.

Keywords

Disease Models, Animal, Ethanol, Liver, Animals, Liver Diseases, Alcoholic

Impact byBIP!

	citations This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	5
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	influence This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).	Average
	impulse This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.	Average