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Bradford Scholars
Article . 2010
Data sources: Bradford Scholars
Journal of Chemical & Engineering Data
Article . 2009 . Peer-reviewed
Data sources: Crossref
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Solubility of Budesonide, Hydrocortisone, and Prednisolone in Ethanol + Water Mixtures at 298.2 K

Authors: Ali, Hany S. M.; York, Peter; Blagden, Nicholas; Soltanpour, Shahla; Acree Jr., William E.; Jouyban, Abolghasem;

Solubility of Budesonide, Hydrocortisone, and Prednisolone in Ethanol + Water Mixtures at 298.2 K

Abstract

Experimental solubilities of budesonide, hydrocortisone, and prednisolone in ethanol + water mixtures at 298.2 K are reported. The solubility of drugs was increased with the addition of ethanol and reached the maximum values of the volume fractions of 90 %, 80 %, and 80 % of ethanol. The Jouyban−Acree model was used to fit the experimental data, and the solubilities were reproduced using previously trained versions of the Jouyban−Acree model and the solubility data in monosolvents in which the overall mean relative deviations (OMRDs) of the models were 5.1 %, 6.4 %, 37.7 %, and 35.9 %, respectively, for the fitted model, the trained version for ethanol + water mixtures, and generally trained versions for various organic solvents + water mixtures. Solubilities were also predicted by a previously established log−linear model of Yalkowsky with the OMRD of 53.8 %.

Countries
United States, United Kingdom, United Kingdom, United Kingdom
Keywords

budesonide, Loglinear model, Hydrocortisone, Prednisolone, 610, Crystal engineering, Experimental data, Solubility data, F100 - Chemistry, Capillary flow, Maximum values, F170 - Physical chemistry, hydrocortisone, Budesonide, Ethanol, 660, prednisolone, Water mixture, Ethanol and water mixtures, Organic solvents, F170 Physical Chemistry, Solubility, Mixtures, Relative deviations, F100 Chemistry, Jouyban-Acree model, ethanol, Regression analysis, Ternary systems

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citations
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
50
Top 10%
Top 10%
Top 10%
Green
bronze
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