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Purple Sweet Potato (Ipomoea batatas L.) Anthocyanins: Preventive Effect on Acute and Subacute Alcoholic Liver Damage and Dealcoholic Effect

doi: 10.1021/jf405032f
pmid: 24564852
This study aimed to investigate the dealcoholic effect and preventive effect of anthocyanins from purple sweet potato (PSPAs) on acute and subacute alcoholic liver damage (ALD). Seven-week-old male inbred mice were grouped into five groups: control group (without PSPAs and ethanol treatments), model group (with ethanol treatment only), low-dose group (50 mg PSPAs/kg body weight), middle-dose group (125 mg PSPAs/kg body weight), and high-dose group (375 mg PSPAs/kg body weight), and the mice in all groups were administered intragastrically. Biochemical parameters of serum and liver were determined, and the histopathological changes of liver tissue were also analyzed. Results showed that all tested parameters were ameliorated after consumption of PSPAs. Therefore, PSPAs have preventive effect on acute and subacute ALD. It is suggested that PSPAs could be used as a supplementary reagent during prophylactic and curative managements of ALD.
- Institute of Agro-Products Processing Science and Technology China (People's Republic of)
- Chinese Academy of Agricultural Sciences China (People's Republic of)
Male, Ethanol, Plant Extracts, Anthocyanins, Mice, Inbred C57BL, Mice, Oxidative Stress, Liver, Animals, Humans, Ipomoea batatas, Liver Diseases, Alcoholic
Male, Ethanol, Plant Extracts, Anthocyanins, Mice, Inbred C57BL, Mice, Oxidative Stress, Liver, Animals, Humans, Ipomoea batatas, Liver Diseases, Alcoholic
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