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Probing impaired neurogenesis in human brain organoids exposed to alcohol

descriptionPublicationkeyboard_double_arrow_right Article , Journal 01 Jan 2017Publisher:Oxford University Press (OUP)Journal:Integrative Biology, volume 9, pages 968-978 (issn: 1757-9694, eissn: 1757-9708,

Authors: Yue Yu; Yue Yu; Zhengping Zhuang; Li Wang; Matthew J. Shepard; Matthew J. Shepard; Fangchao Yin; +7 Authors

doi: 10.1039/c7ib00105c

pmid: 29168871

Probing impaired neurogenesis in human brain organoids exposed to alcohol

- Summary
- Subjects

Abstract

The fetal brain is highly vulnerable to ethanol exposure, which can trigger various long-term neuronal disabilities and cognitive dysfunctions.

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Keywords

Neurogenesis, Induced Pluripotent Stem Cells, In Vitro Techniques, Pregnancy, Neurites, Humans, Hippo Signaling Pathway, Cells, Cultured, Homeodomain Proteins, Neurons, Ethanol, Brain, Cell Differentiation, Organoids, Drug Combinations, Fetal Alcohol Spectrum Disorders, Intercellular Signaling Peptides and Proteins, Female, Collagen, Laminin