The prospects and challenges for non-native tree species (NNTS) in Southeast Europe (SEE) were analyzed using a combination of SWOT Analysis and the Analytic Hierarchy Process (AHP). Preference data from three groups of opinion leaders with extensive knowledge of the silviculture, ecology and impact of climate change on NNTS in SEE (researchers, practitioners and decision-makers) were used. Results revealed that strengths and opportunities for all three analyzed elements outweigh their weaknesses and threats. In the review of silviculture, key strengths and opportunities were identified as high p roductivity, adaptation to afforestation of degraded lands, gap filling in forest ecosystems after the loss of native tree species, and higher volume growth of NNTS compared to native tree species. Strength-Opportunity (SO) elements related to climate change were found to be adaptive management responsiveness to climate change and increased length of growing period, possibility of better-adapted mixtures with NNTS under climate change, and replacement of tree species that are sensitive to pests and outbreaks resulting from climate change. These results provide important insights into different segments of strategy approach of sustainable management of NNTS in relation to management, silviculture and climate change practices in SEE.