Supply chain agility and sustainability is an essential element for the long-term survival and success of a manufacturing organization. Agility is an organization’s ability to respond rapidly to customers’ dynamic demands and volatile market changes. In a dynamic business environment, manufacturing firms demand agility to be evaluated to support any alarming decision. Sustainability is an aspect to sustain collaboration, value creation, and survival of firms under a dynamic competitive business scenario. Agility is a capability that drives competitiveness to foster sustainability aspects. The purpose of this article is to consider and evaluate the supply chain behavior within the context of Saudi enterprises. The efficacy and relevance of this model were explored through a case study conducted in a Saudi dairy manufacturing corporation. Owing to the complexity and a large number of calculations that are required for evaluating the agility of the supply chain, a decision support system was proposed as a tool to assess the supply chain and identifying barriers to a strategic sustainable solution for a specific organizational target. The decision support system is extensive as it contains six separate agility enablers and ninety-three agility attributes for the supply chain. The assessment was carried out using a fuzzy multi-criteria method. It combines the performance rating and importance weight of each agile supply chain-enabler-attribute. To achieve and sustain local and global success, the case organization strove to become a major local and global manufacturer to satisfy its customers, reduce its time to market, lower its total ownership costs, and boost its overall competitiveness through improving its agility across supply chain activities to foster sustainability for a manufacturing organization located in Saudi Arabia.