The processing of meat industry waste into meat-and-bone meal (MBM) provides the opportunity to use it as fertiliser in the cultivation of agricultural crops. This study was conducted in the years 2014–2017 at the Experimental Station in Tomaszkowo, Poland to assess MBM effects on yield and quality of maize cultivated for grain. An example of the effective use of nutrients contained in MBM applied at doses of 2.0 and 3.0 t ha is the cultivation of maize in 2016, which was affected by favourable weather conditions. The effect of the accumulation of MBM doses and, consequently, the provision of a greater amount of nutrients ensure sufficient amounts to obtain yields, greater than those provided by mineral fertilisation only. The macronutrient concentration in the maize grains following the application of MBM was similar to the composition of the grains of maize fertilised with mineral N, P and K fertilisers. With the MBM, micronutrients are introduced in amounts that are able to satisfy plants with these components, yet this study failed to demonstrate any effect of increased MBM doses on the concentration of the analysed elements in the maize grains.