Six iso-nitrogenous (30% crude protein) and iso-energetic (15 kJ g−1) diets were prepared using different oil cake sources, viz. groundnut, soybean, sunflower, sesame, mustard and mixed oil cakes as major ingredients, and protein sources along with a minimum of 5% fish meal in each diet and were fed to silver barb Puntius gonionotus fingerlings (16.20±0.11 g) ad libitum four times a day close to an apparent satiation level for a period of 60 days to determine the effect of diets on growth, nutrient utilization, apparent digestibility coefficient (ADC) of the nutrients in the diets, gut enzyme activity, muscle nucleic acid content and whole-body chemical composition of fish. Significantly higher (P<0.05) weight gain, specific growth rate, protein efficiency ratio, nutrient retention, ADC of nutrients in the diets, DNA:RNA ratio, protease and amylase activity with lower (P<0.05) feed:gain values were recorded in fish-fed groundnut and soybean oil cake-based diets than other diets tested. Among the dietary treatment groups, significantly higher (P<0.05) whole-body protein, lipid and energy were also found in groundnut oil cake- and soybean oil cake-based diets. The study suggests that the groundnut and soybean oil cake-based diets, which led to significantly higher (P<0.05) growth and nutrient utilization than the other oil cake-based diets in P. gonionotus fingerlings, may be used for pond culture of this species.